Zuo-Yue Wu

Mechanisms underlying the reversal of hypoxia-induced energy metabolic reprogramming in cardiomyocytes by Poria cocos triterpenoids: integrated regulation of mitochondrial dynamics and the autophagy–lysosomal pathway

Objective To elucidate the mechanisms by which Poria cocos triterpenoids reverse hypoxia-induced energy metabolic reprogramming in cardiomyocytes through integrated regulation of mitochondrial dynamics and the autophagy–lysosomal pathway. Methods A hypoxic injury model was established in H9c2 rat cardiomyoblasts. Cells...