Orthogonal transforms have emerged as an effective tool for low-bit quantization of large language models (LLMs), as they reshape activation distributions without changing the underlying model function. Existing approaches typically rely either on fixed data-agnostic transforms, such as Hadamard rotations, or on calibr...
Dwaipayan Haldar, I. Patra, Azhar Yousuf et al.· 0 citations
Conditional generative models are increasingly used for scientific prediction beyond the direct training support. Yet scientific questions often concern whether one intervention changes the effect of another. Such interactions can be of primary interest while explaining little of the total variation, allowing models to...
Sam Gijsen, Moritz Seiler, Kerstin Ritter· 0 citations
The Platonic Representation Hypothesis (PRH) holds that increasingly capable models converge toward a common representation. However, recent studies have shown different views on aligning representations via their neighborhoods, spanning trees, and distances. We show that these views can differ because the alignment cr...
Designing RNA sequences that satisfy target tertiary-structure objectives is an important problem in RNA engineering, with broad applications in synthetic biology and therapeutics. Existing 3D RNA design methods have made substantial progress, but they largely treat the target fold as a geometry-only objective. This is...
Tianmeng Hu, Biao Luo, Ke Li· 0 citations
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Learnable downsampling and spectral-domain filter parameterizations have each made convolutional networks more flexible, but their interaction has not been systematically examined. We bridge this gap by examining convolutional kernels learned in the spatial and spectral domains, together with learned downsampling ratio...
FUSE is introduced, a structure-aware robust aggregator that uses a small trusted labeled dataset for coefficient recovery, scale and cone-consistency screening, and post-screening step-size control, and improves seed-wise worst-attack accuracy over the strongest baseline on each benchmark by 3.9--30.1 percentage point...
Deploying a general-purpose model as an agent means running it inside a product-specific runtime harness that decides which actions are executable, how state advances, and when the loop may terminate. Ordinary trajectory supervision shows which action was taken but leaves the runtime semantics behind that action implic...
Junze Zhu, Weihao Chen, Zhiyang Zhou et al.· 0 citations
Long-horizon agents must coordinate reasoning, tool use, and environment feedback over extended interactions. Learning from sparse outcome rewards requires weighting trajectories of different lengths and updating the policy while rollouts are still being collected. We examine a single-rollout asynchronous recipe combin...
Kai Ruan, Jing-Hao Lin, Tao Chen et al.· 0 citations
Deep reinforcement learning (DRL) policies for planetary landing and other aerospace guidance, navigation, and control tasks are commonly trained under randomized disturbances to improve robustness. However, typical stochastic perturbation sampling assumes independent variations, whereas real mission disturbances often...
Miguel Leiva-V\'elez, Nicolas Gaston-Rozado, Andrea Scorsoglio et al.· 0 citations
Anomaly detection is a fundamental task for time-series analytics, with important implications for the downstream performance of many applications. Despite the large number of anomaly detection methods proposed in the literature, recent benchmark studies have shown that no single detector performs best across highly he...
Christos Panourgias, Roberto Stanzione, Adrien Petralia et al.· 0 citations
This work proposes MAEM, a replay-free, capacity-controlled dynamic mixture-of-experts framework for class-incremental graph learning that mitigates recency bias, outperforms strong continual graph learning baselines, and keeps model capacity bounded under strict replay-free learning.
Jun-Lin Chen, Wen-Hao Wang, Jun Xu et al.· 0 citations
HGRP models the cells, nets, and routing grids as distinct types of nodes and explicitly represents topological connectivity, spatial mapping, and grid adjacency, thereby constructing a heterogeneous graph representation that preserves multi-level circuit semantics.
Yu-Le Sheng, Yue Yuan, Shan Shen et al.· 0 citations
A machine-learning approach called CheMeleon provides a practical way to develop new drugs or other molecules with much less detailed, expensive experimentation.
Research Manager Mike Walker reflects on a career spanning hacker culture, cybersecurity, and AI, sharing lessons about trust, teamwork, leadership, and why solving difficult problems requires curiosity, judgment, agility—and an understanding of the rules. The post Learn the rules: The hacker mindset appeared first on Microsoft Research.
Learn how Google Antigravity and our Cheminformatics Skills accelerate drug discovery workflows, search compounds, and propose novel rigidified macrocycles.
MIT News · Artificial Intelligence· news.mit.eduOct 28, 2026
Professor Paris Smaragdis develops computers with superhuman hearing for applications like speech recognition, music understanding, and environmental monitoring.
MIT News · Artificial Intelligence· news.mit.eduOct 27, 2026
Prabha Jha used her experience with MIT Open Learning’s program for senior executives to develop AI solutions for her employer, Verizon, and to write a book.
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