We examine whether human psychometric questionnaires can serve as reliable tools for characterizing and predicting LLM behavior in everyday user interactions. We analyze eight open-source LLMs by comparing their value and personality profiles derived from two different methods: Likert self-reports on established questionnaires (PVQ-40/21 and BFI-44/10) and generation probabilities over value-laden responses to everyday user queries. The two profiles diverge substantially. Within-construct item consistency, often cited as evidence of stable LLM dispositions, disappears in generation probabilities. We find that established questionnaire items contain explicit lexical cues that allow models to recognize the target construct and respond in alignment-consistent, socially desirable ways, whereas realistic user queries contain far less recognizable cues. In addition, demographic persona prompts shift models' responses to human questionnaires in ways consistent with real human patterns, but no such shifts appear in the generation setting, highlighting that human questionnaires overestimate LLMs' ability to faithfully reproduce expected psychological traits when role-playing demographic personas. Overall, our study indicates that questionnaire scores alone should not be treated as evidence of LLMs' response tendencies in realistic user interactions, and supports generation-probability profiling with ecologically valid items as a complementary behavioral measure.
Woojung Song, Dongmin Choi, Yoonah Park et al.· 0 citations
The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice. This has catalyzed a shift from single-step answer generation to the development of LLMs explicitly designed for medical reasoning. This paper provides the first systematic review of this emerging field. We propose a taxonomy of reasoning enhancement techniques, categorized into training-time strategies (e.g., supervised fine-tuning, reinforcement learning) and test-time mechanisms (e.g., prompt engineering, multi-agent systems). We analyze how these techniques are applied across different data modalities (text, image, code) and in key clinical applications such as diagnosis, education, and treatment planning. Furthermore, we survey the evolution of evaluation benchmarks from simple accuracy metrics to sophisticated assessments of reasoning quality and visual interpretability. Based on an analysis of 60 seminal studies from 2022-2025, we conclude by identifying critical challenges, including the faithfulness-plausibility gap and the need for native multimodal reasoning, and outlining future directions toward building efficient, robust, and sociotechnically responsible medical AI.
Zizhan Ma, Wenxuan Wang, Meidan Ding et al.· 0 citations
Existing LLM-based agents have achieved strong performance on held-in tasks, but their generalizability to unseen tasks remains poor. Hence, some recent work focus on fine-tuning the policy model with more diverse tasks to improve the generalizability. In this work, we find that finetuning a reward model to guide the policy model is more robust than directly finetuning the policy model. Based on this finding, we propose AgentRM, a generalizable reward model, to guide the policy model for effective test-time search. We comprehensively investigate three approaches to construct the reward model, including explicit reward modeling, implicit reward modeling and LLM-as-a-judge. We then use AgentRM to guide the answer generation with Best-of-N sampling and step-level beam search. On four types of nine agent tasks, AgentRM enhances the base policy model by $8.8$ points on average, surpassing the top general agent by $4.0$. Moreover, it demonstrates weak-to-strong generalization, yielding greater improvement of $12.6$ on LLaMA-3-70B policy model. As for the specializability, AgentRM can also boost a finetuned policy model and outperform the top specialized agent by $11.4$ on three held-in tasks. Further analysis verifies its effectiveness in test-time scaling. Codes will be released to facilitate the research in this area.
Yu Xia, Jingru Fan, Weize Chen et al.· 0 citations
Recent advancements in large language models (LLMs) have demonstrated their potential in automating the scientific research ideation. Existing approaches primarily focus on prompting techniques, often producing ideas misaligned with expert standards - novelty, feasibility, and effectiveness, which are widely recognized by the research community as the three key subdimensions of high-quality ideas. Also, balancing these dimensions remains challenging due to their inherent trade-offs. To address these limitations, we propose the first framework that employs a two-stage approach combining Supervised Fine-Tuning (SFT) and controllable Reinforcement Learning (RL) for the task. In the SFT stage, the model learns foundational patterns from pairs of research papers and their corresponding follow-up ideas. In the RL stage, multi-dimensional reward models guided by fine-grained feedback evaluate and optimize the model across key dimensions. During inference, dimensional controllers coordinated by a sentence-level decoder enable dynamic context-aware steering of the idea generation process. Our framework provides a balanced approach to research idea generation, achieving high-quality outcomes in the experiment by dynamically navigating the trade-offs among novelty, feasibility, and effectiveness.
Ruochen Li, Liqiang Jing, Chi Han et al.· 0 citations
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Omni-modal dialogue models can understand multimodal inputs and synthesize spoken replies, but a spoken answer still leaves the agent visually absent. We introduce \textbf{Ex-Omni-2D}, a framework that answers a multimodal query with coordinated text, personalized speech, and reference-conditioned video. The dialogue model first writes a structured \textit{Visual Thought Plan} (VTP) for scene, emotion, and motion, then generates the response text and multi-codebook speech units. These speech units are decoded into audio and aligned with video frames, giving the speech and avatar modules a common timing signal while allowing them to learn from different data sources. The video module is trained as a full-sequence Teacher conditioned on reference appearance, VTP semantics, and frame-aligned speech units. We further explore to distill it into a few-step block-causal \emph{Streaming Student}; its Prefix Streaming mechanism carries the previous clean latent into the next chunk and is analyzed as a partial mitigation for late-chunk subject drift. At $400\times720$/$720\times400$, the four-step four-GPU Student provides incremental output with lower startup latency than the full-sequence Teacher.
Haoyu Zhang, Zhipeng Li, Xiaoying Tang et al.· 0 citations
Large language models can answer scientific questions, yet a correct output does not reveal whether the model represents or uses the governing physics. Here, using three open-weight Gemma 4 models (google/gemma-4-E4B-it, google/gemma-4-12B-it, google/gemma-4-31B-it) we identify three experimentally separable signatures of materials-science mechanism information: selective concept readability, relational encoding of qualitative constitutive orientation, and causal, context-dependent control of constrained engineering answers. We combine matched direct and Jacobian vocabulary readouts, option-free state geometry, a 60-law counterfactual benchmark and causal interventions. In 50 held-out materials descriptions, three independently fitted Jacobian lenses reproduced concept ranks, and target-free word sets from both readouts enabled blinded identification of 9 of 10 mechanism families. A separate 72-prompt benchmark produced mechanism-specific hidden-state neighborhoods, but an exact graph audit showed that this apparent physical organization was equally explained by numerical comparison. We therefore compared otherwise identical prompts in which only the direction of the physical input was reversed, asking whether the resulting hidden-state movement followed the supplied constitutive law. These state transformations ordered direct, physically neutral and inverse laws across 60 frozen relations and correctly oriented 39 of 40 directional laws, whereas lexical controls were near chance. Bidirectional interventions shifted answer probabilities toward or away from the physically appropriate outcome across all 12 matched cases, while counterfactual state patches transferred opposing decision signals across mechanisms and answer formats. Physical relationships were therefore more visible in controlled state changes than in absolute states alone.
Background: Oral diseases affect nearly 3.5 billion people worldwide, yet the comparative clinical potential of large-scale AI models in dentistry remains poorly understood. Three distinct model categories have emerged: language-generative models, discriminative vision foundation models, and dental-specific foundation models, with no unified review examining their relationships and collective limitations.
Methods: Following PRISMA-ScR guidelines, we systematically searched four databases (PubMed, Google Scholar, Scopus, arXiv), screened independently by two reviewers. After applying inclusion/exclusion criteria, 97 studies (2020-2026) were included. We propose a two-dimensional classification framework organizing models by architectural paradigm and dental specialization degree.
Results: Language-generative models excel at text-based tasks (clinical reasoning, licensing exams, patient communication) but show inconsistent performance on image-dependent diagnostics. Adapted SAM and CLIP variants achieve strong tooth segmentation and lesion detection results. Dental-specific models (DentVFM, DentVLM, OralGPT) demonstrate strongest performance on complex multimodal tasks. Integrated pipelines consistently outperform single-model approaches. A data asymmetry is observed: dental-specific pretraining concentrates almost entirely in the vision domain, reflecting scarce large-scale dental text corpora.
Conclusions: General-purpose and dental-specific models play complementary roles; the most effective systems combine both within structured pipelines. Safe autonomous deployment requires resolving three persistent barriers: hallucination in generative models, limited annotated dental datasets, and absent standardized clinical evaluation benchmarks.
Sema Helali, Lina Abu Nada, Sausan Al Kawas et al.· 0 citations
Equipping language agents with world models enables them to anticipate environment dynamics and evaluate candidate actions before execution. However, existing textual world models are typically fixed after training, preventing them from adapting to the on-policy state-action distributions induced by an evolving agent. Meanwhile, agent-improvement methods often rely on external rewards or verifiers, limiting their applicability in realistic interactive environments. In this paper, we propose COMAP, a novel framework that co-evolves textual world models and agent policies through closed-loop interaction. At each decision step, the world model predicts future state feedback for candidate actions, and the agent performs future-aware reflection by estimating the reliability of this feedback and refining its action accordingly. The resulting on-policy trajectories are then used to update the world model via self-distillation, allowing it to better match the agent's evolving interaction distribution. Across embodied task planning, Web navigation, and tool-use benchmarks, COMAP consistently outperforms competitive baselines, e.g., +16.75% relative improvement with Qwen3-4B. Further analyses show that the co-evolutionary loop improves the world model's prediction accuracy over time and leads to more effective long-horizon decision-making. Our code is available at: https://github.com/loyiv/CoMAP.
Youwei Liu, Jian Wang, Hanlin Wang et al.· 0 citations
Existing safety evaluations for large language models overlook whether responses preserve comparable medical information across different user phrasings of the same question. To address this, we introduce the Medical Information Response Audit (MIRA), a bilingual, controlled benchmark that assesses whether LLMs provide comparable medical information across user-side language, register, and health literacy signals. MIRA contains 4,320 prompts built from 60 medically reviewed, low-risk health questions. Across five mainstream LLMs, models answered all medical questions, but responses to low health-literacy signals consistently omitted more key information, provided fewer concrete next steps, and offered less support for independent judgment. We term this pattern Differential Information Dilution (DID). A comparison with 300 real-world health queries provides preliminary evidence of rank-order validity. A knowledge-guided mitigation prompt reduces information dilution for most models, with the largest reductions in underinformative simplification observed for Claude (~8%) and Qwen (~6%). Code and data are available at https://github.com/Rainxu09/MIRA.
Mengyu Xu, Qiaoxin Yang, Qianqian Wang et al.· 0 citations
Large Language Models (LLMs) struggle with reliably generating highly structured outputs, such as program code, mathematical formulas, or well-formed markup. Constrained decoding approaches mitigate this problem by greedily restricting what tokens an LLM can output at each step to guarantee that the output matches a given constraint. Specifically, in grammar-constrained decoding (GCD), the LLM's output must follow a given grammar. In this paper, we demonstrate that GCD techniques (and in general constrained decoding techniques) can distort the LLM's distribution, leading to outputs that are grammatical but appear with likelihoods that are not proportional to the ones given by the LLM, and so ultimately are low-quality. We call the problem of aligning sampling with a grammar constraint, grammar-aligned decoding (GAD), and propose adaptive sampling with approximate expected futures (ASAp), a decoding algorithm that guarantees the output to be grammatical while provably producing outputs that match the conditional probability of the LLM's distribution conditioned on the given grammar constraint. Our algorithm uses prior sample outputs to soundly overapproximate the future grammaticality of different output prefixes. Our evaluation on code generation and structured NLP tasks shows how ASAp often produces outputs with higher likelihood (according to the LLM's distribution) than existing GCD techniques, while still enforcing the desired grammatical constraints.
Kanghee Park, Jiayu Wang, Taylor Berg-Kirkpatrick et al.· 0 citations
Many recurring text functions are easy to describe but difficult to implement with rules, while calling a large remote model for every input introduces repeated cost, latency, and dependency on a provider. We present compile by training, which turns a natural-language specification into a reusable neural function. At compile time, teacher models generate task-specific examples that are used to train a small adapter for a compact interpreter. The resulting function runs without the teachers and can be stored, versioned, and composed like ordinary software. On FuzzyBench-Hard, a subset on which the Program-as-Weights fast compiler produced no exact matches, compile by training reaches 83.6% semantic accuracy. This higher accuracy comes with a higher compile-time cost: roughly a minute rather than seconds for the fast compiler. We deploy the compiler in a public interactive service and demonstrate compiled functions in a multi-site website helper, a language-controlled 3D avatar, and a bidirectional English-Claudish translator.
Yuntian Deng, Pengyu Nie, Stuart Shieber· 0 citations
Evolutionary prompt optimizers such as GEPA suffer from prompt bloat: each iteration appends rules and caveats, producing prompts up to 3$\times$ longer yet no more accurate. We trace this to three deficiencies - incomplete error observation, limited search diversity, and unreliable selection - and propose ESPO (Error-Structured Prompt Optimization), which decomposes prompt optimization into three phases: Diagnose clusters all training errors into structural patterns in one round; Propose generates candidates via four complementary strategies with independent biases; Select applies bootstrap stability selection. On seven public NLP benchmarks - Tweet, MMLU, GSM8K, HotpotQA, ScoNe, HoVer, and PUPA - ESPO improves average accuracy by $+$3.76 pp over the state-of-the-art (74.67% vs 70.91% for GEPA), matching or exceeding GEPA on every dataset while producing prompts 47% shorter (1,004 vs 1,878 chars) and faster at inference. Cross-model experiments across four additional student models (Gemma 3 12B, Mistral 14B, Qwen3 32B, Claude Haiku 4.5) show ESPO yields the best average accuracy on every model tested, with the largest gap on Qwen3 GSM8K (15.00% $\to$ 91.40%). A generalization bound (Appendix) grounds each phase in a corresponding term of the test-time gap, and the ablation confirms a key prediction: adding diversity without bootstrap selection actually hurts performance ($-$1.20%).
A new method, called CW-Net, translates the reasoning process of an autonomous vehicle’s AI system into understandable concepts that explain its behavior.
MIT News · Artificial Intelligence· news.mit.eduAug 31, 2026
With millions of users across the world, Julia has been used to conduct cutting-edge research and to design new drugs, jet engines, heat pumps, and more.
A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.
New MIT research could lead to better materials for a fossil-fuel-free process for making the chemical that's essential to fertilizer and other products.
