Aug 2026· Healthway· Vol 2, pp. 223-228· 0 citations
TL;DR
VNS therapy represents a safe and effective adjunctive treatment option for DRE during pregnancy when resective surgery is not feasible and resulted in complete seizure remission and transition to levetiracetam monotherapy.
Abstract
Abstract. Introduction. Drug-resistant epilepsy (DRE) affects approximately 30% of patients and poses significant challenges during pregnancy due to seizure-related risks and antiepileptic drug teratogenicity.Objective. To report the first case in the Russian Federation of successful vagus nerve stimulator implantation patient with during in DRE.pregnancy a Materials and Methods. A clinical case of a 28-year-old woman with an 11-year history of DRE who underwent VNS implantation is presented.weeks gestation of at 18 Results. Gradual activation of the stimulator resulted in complete seizure remission and transition to levetiracetam monotherapy. Pregnancy and delivery were uneventful, resulting in the birth of a healthy child.Conclusion. VNS therapy represents a safe and effective adjunctive treatment option for DRE during pregnancy when resective surgery is not feasible.
ABSTRACT There are limited reports on vagus nerve stimulation (VNS) therapy during pregnancy. We report a case of two pregnancies in a woman with drug‐resistant epilepsy (DRE) managed with VNS. A woman with epilepsy underwent implantation of a VNS device because antiseizure medications (ASMs) and a lobectomy were not s...
Motoki Ono, R. Asaka, Yasuhiro Tanaka et al.· Clinical Case Reports· 0 citations
Drug-resistant epilepsy affects approximately one-third of patients and is often not amenable to resective surgery due to the bilateral nature of the epileptogenic network, multifocality, or localization of the seizure onset zone within eloquent cortical areas. In such cases, neuromodulation techniques are preferable,...
D. Sevastyanov, A. Kholyavin· Vestnik nevrologii, psihiatr...· 0 citations
Background Vagus nerve stimulation is an established therapeutic option for children with drug-resistant epilepsy who do not respond to other treatments. During surgical procedures, this therapy has various anesthetic implications and may result in critical respiratory and cardiac complications. Case We report the case...
R. E. Rebollar, José Manuel Muñoz Quintero, Rafael Eduardo López Alfaro· Korean Journal of Anesthesio...· 0 citations
The evidence for a monoamine hypothesis of VNS function is proposed and a clearer understanding of this mechanism of action (MOA) can help clinicians work with patients to make more informed treatment decisions.
Objective
Vagus nerve stimulation (VNS) is an established adjunctive therapy for drug-resistant epilepsy (DRE). Although its long-term efficacy after electrical activation is well recognized, transient seizure reduction has occasionally been observed immediately after implantation, even before stimulation onset. This s...
Jong-Young Park, Kawngwoo Park, J. Jung et al.· Journal of Korean Neurosurgi...· 0 citations
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