Baseline systolic blood pressure and longitudinal increase in HbA1c levels as predictors of bone mineral density in older men: a 4-year prospective study
Findings suggest that commonly assessed metabolic indicators may provide useful predictive information for identifying older men at risk of low BMD, highlighting the importance of vascular and metabolic health in skeletal aging.
No routinely measured biomarker demonstrated clinical utility for identifying BMD trajectory in this cohort of Saudi dual-energy X-ray absorptiometry patients, suggesting future studies with explicit treatment tracking and repeated bone-turnover measurements are required for confirmation.
L. Jambi, S. Kabrah· Journal of Clinical Medicine· 0 citations
Background The triglyceride-glucose (TyG) index and its derivatives are cost-effective markers of insulin resistance and cardiovascular risk. However, the comparative predictive value of baseline levels, cumulative exposure, and annual mean changes in TyG-related indices remains unclear. This study aimed to systematica...
Yang-Zhen Xue, Qing-Xiu Tian, Rong Zhang et al.· Frontiers in Endocrinology· 0 citations
Increases in BMI and WHtR were consistently associated with higher risks of hypertension, dyslipidemia, hyperuricemia, hyperuricemia, and early CKM stage progression across baseline body size categories.
Shinta Yamamoto, Hiroshi Okada, Tomohiro Shinozaki et al.· Diabetes, obesity and metabo...· 0 citations
In this exploratory analysis, nutrition-related anthropometric measures, poorer pulmonary function, and exercise-induced desaturation were associated with the long-term decline in PA, and a lower BMI remained associated after adjustment.
Yusuke Murakami, Yoshiaki Minakata, Yasushi Tanimoto et al.· Journal of Clinical Medicine· 0 citations
OBJECTIVE
Active vitamin D analogs increase bone mineral density (BMD), but inter-individual variability in skeletal response remains unexplained. Emerging evidence suggests skeletal remodeling is influenced by systemic metabolic status. Therefore, we examined whether metabolic state, defined by glycemic trajectory, mo...
Tetsuya Kawahara, Mikio Toda, Maiko Kanagawa et al.· Journal of Clinical Endocrin...· 0 citations
In cancer patients, higher METS-IR is independently associated with greater BMD but not with better trabecular microarchitecture, suggesting that insulin resistance may mask impaired bone quality despite preserved BMD.
Hong-Dan Yao, Cheng Niu, Lin Zhu et al.· Frontiers in Endocrinology· 0 citations
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