TL;DR
The developed chitosan-coated Eudragit® S100 nanoparticle system represents a promising platform for sustained, colon-targeted oral delivery of HSP and other poorly bioavailable bioactive compounds.
Purpose The main purpose of the present study was to explore chitosan as a polymeric material for the preparation of vonoprazan nanoparticles intended for use as a delivery system for acid-related diseases. Methods Vonoprazan-loaded chitosan nanoparticles were formulated using the ionotropic gelation method and charact...
The clinical utility of lamotrigine in epilepsy is limited by poor aqueous solubility, variable oral absorption, short half-life, and P-glycoprotein-mediated efflux at the blood-brain barrier. This study aimed to develop an optimized chitosan-sodium alginate polymeric nanoparticle system for Lamotrigine with desire...
Evidence from recent studies demonstrates that MSNs significantly improve drug loading efficiency, enhance solubility and bioavailability, and reduce off-target toxicity, Consequently, MSNs represent a highly versatile and modifiable platform with considerable potential for addressing the limitations of conventional dr...
Curcumin's application is severely hindered by its hydrophobicity, poor solubility and rapid degradation. This study developed a pH-responsive, dual-layered curcumin-chitosan nanoemulsion (nCCURs) system using the phase inversion temperature method coupled with probe ultrasonication. The platform comprises a curcumin...
Nanoemulgel technology has been widely recognized for its potential to design efficient topical dosage forms by leveraging the solubilizing properties of nanoemulsions and the advantageous application properties of gels. This synergy is highly advantageous for countering the drawbacks of conventional topical formulatio...
We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.
