The CYP1A1 rs1048943 polymorphism was not associated with laryngeal cancer susceptibility in this Sudanese cohort, and larger studies are needed to clarify the genetic basis of laryngeal carcinogenesis.
Marwa Abdalwahab, M. Ellaithi· F1000Research· 0 citations
Objective Caspase-8 (CASP8) is essential for apoptotic clearance of transformed cells and is encoded by the CASP8 gene. The CASP8 -652 6N del polymorphism (rs3834129) has been studied in relation to colorectal cancer (CRC) risk with conflicting outcomes. This meta-analysis aims to provide a consolidated assessment of t...
Jun Wang, C. Ye· Medeniyet Medical Journal· 0 citations
Background/Aim: Colorectal cancer is the second most common cancer in women and the third most common in men. It is the third leading cause of cancer death worldwide. Statistics suggest a worrying increase in the incidence of this cancer in the coming years. Many factors, including family history, age, smoking habits a...
Mohammad Javan-Fekr, Mohammad-Hossein Sabzevari, I. Saadat· Scripta Medica· 0 citations
Background Cytochrome P450 3A5 (CYP3A5) is a key xenobiotic‐metabolizing enzyme that also participates in the biotransformation of endogenous substrates. Functional genetic variation within CYP3A5 can alter enzyme activity and may consequently modify individual susceptibility to malignancy. The contribution of CYP3A5 g...
It is suggested that SYNE1 rs2295190 may be associated with OSCC progression rather than overall disease susceptibility, particularly in the context of betel quid exposure.
Ming-Ju Hsieh, Hsin-Yu Ho, Yu-Sheng Lo et al.· Journal of Cancer· 0 citations
Exonuclease 1 (
EXO1
) is a key nuclease in the DNA mismatch repair (MMR) pathway and is involved in correcting replication errors while maintaining genomic stability. The K589E (rs1047840) single nucleotide polymorphism (SNP) of
EXO1
has been associated with cancer susceptibility in different populations....
Mahmudul Kabir, M. Rahman, Sm Faysal Bellah et al.· Breast Cancer: Basic and Cli...· 0 citations
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