TL;DR
The findings suggest that CT contributes to chronic pain vulnerability partly through accelerated biological aging pathways, particularly in women.
Background: Major depressive disorder (MDD) is associated with brain dysfunction and age-related diseases. Epigenetic clocks based on DNA methylation patterns estimate biological aging and aim to predict morbidity and mortality. Although MDD has been linked to epigenetic age acceleration (EAA) cross-sectionally, it is...
Both cBMI and cWC were positively associated with KDM-BA and PD in Chinese older adults, and a potential modifying effect of genetic susceptibility to longevity on the associations between cWC and KDM-BA was observed.
This review evaluates the impact of Post-Acute Sequelae of SARS-CoV-2 on adults aged 25 to 55, focusing on the potential for accelerated biological aging and an increased incidence of acute cardiovascular events. By synthesizing evidence from 110 epidemiological and mechanistic studies, we examine the interplay between...
OBJECTIVE Adverse childhood experiences (ACEs) are strong risk factors for biological dysregulation, morbidity, and mortality over the lifespan. Although research has begun investigating potential risk and resilience processes that mediate and moderate these associations, little research has examined the unique role th...
Recent lifespan frameworks of aging theorize that pubertal development and cellular aging are governed by overlapping pathways, but the time lag between adolescence and older adulthood complicates the study of shared molecular mechanisms. Here we compare a DNA-methylation-based epigenetic index of pubertal development...
Background: A gap between biological and chronological age known as "accelerated aging" has become a quantifiable phenomenon associated with modifiable features of modern urban and industrial environments. Two or more of the following factors linked to premature biological aging, independent of chronological age: envir...
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