The diagnostic accuracy of D-dimer testing varies significantly across subgroups defined by the Wells score, and the D-dimer test positivity threshold could be adapted to keep specificity more comparable across all values on the Wells score.
ObjectivesTo investigate the prognostic value of the systemic immune-inflammation index (SII), lactate-to-albumin ratio (LAR), and D-dimer for in-hospital adverse outcomes in patients with acute pulmonary embolism (APE).MethodsThis single-center retrospective cohort study screened 248 patients with computed tomography...
Zi-Xuan Chen, Si-Jia Huang, Yu-Xiao Song et al.· Clinical and applied thrombo...· 0 citations
BACKGROUND
Pulmonary embolism (PE) is a potentially life-threatening condition requiring rapid diagnosis and management. While computed tomography pulmonary angiography (CTPA) is the gold standard for diagnosis, its overuse raises concerns about radiation exposure and healthcare costs. The objective of this study was t...
B. Gülen, Hİ. Celik, G. Bozkuş et al.· Clinical Laboratory· 0 citations
A threshold of 1050 μg/L FEU, validated in two very old geriatric cohorts, offers a safer and more specific alternative for ruling out PE in geriatric emergency care.
F. Marchegiani, R. Galeazzi, L. Antognoli et al.· Thrombosis Research· 0 citations
BACKGROUND
Current pulmonary embolism (PE) guidelines support outpatient management for selected low-risk patients, typically identified using the simplified Pulmonary Embolism Severity Index (sPESI). The prognostic value of individual sPESI scores in the direct oral anticoagulant (DOAC) era, particularly when combined...
Michael M. Dore, Ryan Duffy, Omar Melikechi· Academic Emergency Medicine· 0 citations
Background/Objectives: Early risk stratification is essential in pulmonary embolism (PE), but a simple tool integrating routinely available clinical and laboratory variables is lacking. We aimed to develop a simple score for predicting 30-day mortality in patients presenting to the emergency department (ED) with PE. Me...
Shin Young Park, I. Park, H. Chung et al.· Diagnostics· 0 citations
BACKGROUND
Adaptive D-dimer strategies for rule out of pulmonary embolism (PE) have been proposed to improve the efficiency of conventional fixed '500' D-dimer thresholds. Validations of adaptive D-dimer strategies post-hoc in cohorts managed according to the fixed D-dimer threshold seems to questions their safety. Res...
Mara Graziani, B. Akerboom, Y. Freund et al.· Chest· 1 citation
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