Assessment Of Left Ventricular Filling Pressure Using EchocardiographyAmong Patients With Chronic Kidney Disease: AProspectiveCross-Sectional Observational study
2026· INDIAN JOURNAL OF ALLIED HEALTH SCIENCE· Vol 02, pp. 251-264· 0 citations
TL;DR
Tissue Doppler Imaging (TDI)-derived E/e′ ratio is a valuable non-invasive tool for assessing LVFP and identifying early cardiac dysfunction in CKD patients.
Abstract
Background: Chronic kidney disease (CKD) is associated with an increasedriskofcardiovascular disease, with left ventricular diastolic dysfunction occurring earlyindiseaseprogression. Tissue Doppler Imaging (TDI)-derived E/e′ ratio is a reliable non-invasivemarkerof left ventricular filling pressure (LVFP). Methods: This prospective cross-sectional study included 33 adults with CKDStages3–5.Transthoracic echocardiography with TDI was performed to assess LVFP usingtheE/e′ ratio.The association between LVFP and CKD stage was analyzed using the Chi-squaretest. Results: The mean age was 51.55 ± 11.68 years, and 60.6% were males. Stage 5CKDwasmostcommon (51.5%). Normal LVFP was observed in 60.6% of patients, while 39.4%hadabnormalLVFP. The mean E/e′ ratio was 8.17 ± 3.12, and mean left ventricular ejectionfractionwas50.91 ± 9.32%. No significant association was found between CKDstage andLVFP(p=0.626). Conclusion: TDI-derived E/e′ ratio is a valuable non-invasive tool for assessingLVFPandidentifying early cardiac dysfunction in CKD patients.
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BACKGROUND
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