[Treatment of Hypercholesterolemia in Chronic Kidney Disease: Rationale and Therapeutic Approaches from the Non-Dialysis Stage to Kidney Transplantation].
Aug 2026· Giornale Italiano di Nefrologia· Vol 43 4· 0 citations
Medicine
TL;DR
The role of low-density lipoprotein cholesterol (LDL-C) in the excess cardiovascular risk associated with CKD is addressed and the impact of both traditional and novel LDL-C-lowering therapies across the entire spectrum of CKD is examined.
An overview of domestic and international guidelines for dyslipidemia is provided and the association between dyslipidemia and ischemic stroke is summarized from the perspectives of pathophysiology, pathological findings, and imaging and blood biomarker.
Junya Aoki· Journal of atherosclerosis a...· 0 citations
It is concluded that secondary causes must be ruled out upon diagnosis and non-HDL cholesterol is highlighted as a critical secondary therapeutic target for comprehensive cardiovascular risk management.
L. Popović, Sandra Singh-Lukač, I. Rasulić et al.· Medicinska istrazivanja· 0 citations
Treatment paradigms emphasize early intensification of therapy and addition of non-statin agents, and polygenic risk scoring and RNA-based therapies may offer opportunities to identify and treat those at highest residual risk.
Andrew Carlson, Zaid A. Zayyad, Stefanie Driesenga et al.· Cardiology and Therapy· 0 citations
High-risk dyslipidemia is a treatment problem defined less by an isolated cholesterol value than by the interaction between atherogenic lipoprotein burden and absolute cardiovascular risk. This structured narrative review examines contemporary lipid targets, the role of high-intensity statins, and the place of newer li...
F. D. de Souza, Laura Leme de Araújo Rodrigues da Silva, Nicolas Victor Camargo Chon et al.· International Health Science...· 0 citations
Patients with chronic kidney disease (CKD) have a disproportionate burden of cardiovascular disease, and the majority die from cardiovascular causes before ever reaching kidney failure. Atherosclerotic cardiovascular disease (ASCVD), which includes coronary artery disease, cerebrovascular disease, and peripheral arteri...
Simon Correa, Jonathan W. Cuningham, F. M. Mc Causland· American Society of Nephrolo...· 0 citations
