Skip to content
Open access

Air pollution drives concentrated clinical severity of respiratory illness in early childhood

Sep 2026 · medRxiv · 0 citations
Medicine

TL;DR

Air pollution imposes a dual burden, amplifying both the frequency and severity of illness among the youngest infants, and a shift towards higher-intensity emergency care among children under 5.

Abstract

Exposure to fine particulate matter (PM2.5) increases paediatric respiratory morbidity, but its impact on the intensity and economic burden of care in early childhood remains unclear. Here we link nationwide health records for 3,210,381 South Korean children (99,261,945 child-month observations, 2015-2019) and exploit quasi-random variation in PM2.5 induced by thermal inversions to estimate its causal effects on respiratory care and expenditure. A 1-standard-deviation increase in monthly PM2.5 (7.23 micrograms per cubic metre) raises respiratory visits broadly, peaking at age 1 (0.29 additional visits per child-month) and remaining significant through age 6. In contrast, expenditures rise disproportionately among children under 3, increasing by 46.7%, 43.0%, and 35.4% at ages 0, 1, and 2 and becoming indistinguishable from zero beyond age 4. This shift towards higher-intensity emergency care translates into a 32.2% increase in annual respiratory spending among children under 5. Air pollution thus imposes a dual burden, amplifying both the frequency and severity of illness among the youngest infants.

Read PDF

Similar papers

Review Open access Aug 2026

Environmental Determinants of Respiratory Diseases: Current Evidence and Preventive Strategies

The deterioration of ambient air quality worldwide has intensified the need to examine the environmental factors associated with the growing burden of respiratory disease. This study aimed to identify broad patterns in the adverse effects of environmental exposures on the respiratory system, while accounting for region...

Zhanibek Muratov, Aida Zotaj, A. Kalandarova et al. · 0 citations
Open access Sep 2026

The impact of London's Ultra Low Emission Zone on respiratory prescribing: a synthetic control study

Urban air pollution remains a significant public health concern, contributing to premature deaths and adverse health outcomes. However, there is little causal research evaluating the effectiveness of policies designed to improve air quality. This study assesses the impact of all three stages of London's Ultra Low Emiss...

G. H. Williams, T. Allen · 0 citations
Open access Sep 2026

Early-Life Exposure to Ambient Air Pollution and Respiratory Outcomes: Mixture and Sex-Stratified Associations with Inflammatory Cytokine Responses.

PM2.5 is the primary predictor of respiratory outcomes and inflammatory responses during the first year of life, and whether these are modified by sex and temperature is investigated.

S. Gómez-Olarte, S. Röder, K. de Hoogh et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.