This review critically synthesizes advances across omics techniques including epigenomics, transcriptomics, metabolomics and proteomics and their integration and evaluates using case studies when additional molecular layers provide critical insight and when they offer limited advantage, a strategic distinction with direct implications in environmental monitoring programmes.
A mechanistic analysis of pharmaceutical ecotoxicity demonstrates that effective intervention requires targeting root causes across the pharmaceutical lifecycle rather than relying on end-of-pipe remediation, and that integrating environmental sustainability into pharmaceutical safety assessment is essential for protec...
Yu-Jian Fan, Xiao-Kai Guo, Jiaying Lyu et al.· Ecotoxicology and Environmen...· 0 citations
Mycotoxins are widespread environmental contaminants whose global prevalence and ecological impacts are intensifying due to climate change. However, their sublethal effects on wildlife populations and ecosystem stability remain significantly underexplored. Laboratory studies have demonstrated that mycotoxins induce epi...
Hira Sayed, Saber Y. Adam, Syeda Amna Batool et al.· Environmental Toxicology and...· 0 citations
The field of aquatic toxicology has undergone a paradigm shift in recent decades. The movement away from observational data detailing the concentrations that produce deleterious effects and towards a mechanistic understanding of how toxicants affect organismal physiology has significant advantages for the field. This m...
T. Blewett, C. N. Glover, Erin M. Leonard et al.· Journal of Experimental Biol...· 0 citations
The rapid advancement of nanotechnology has outpaced the development of adequate toxicity assessment methods, necessitating innovative analytical frameworks for evaluating emerging nano-contaminants. The zebrafish (Danio rerio) has emerged as a versatile vertebrate model that enables a comprehensive evaluation of molec...
S. N. E. Sarchio, S. Shamsi· Journal of Applied Toxicolog...· 0 citations
Holistic protection goals in environmental hazard and risk assessment, complex pollutant mixtures, and limitations in targeted chemical analysis highlight the need for robust, mechanistically informative bioanalytics to support water quality monitoring. Given the scarcity of high-throughput, non-mammalian in vitro effe...
S. Lungu-Mitea, G. Mandava, J. Horáčková et al.· Ecotoxicology and Environmen...· 0 citations
Emerging contaminants (ECs), such as pharmaceuticals, microplastics (MPs), per- and polyfluoroalkyl substances (PFAS), polycyclic aromatic hydrocarbons (PAH), endocrine-disrupting compounds (EDC) and heavy metals, are progressively affecting soil ecosystems through multiple inputs such as wastewater irrigation, biosoli...
K. S. Kiran, M. Elayarajan, S. Suganya et al.· Plant Science Today· 0 citations
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