Aug 2026· The Veterinary clinics of North America. Small animal practice· Vol 56, pp. 1205-1224· 0 citations· 107 references
Medicine
TL;DR
Sustainable control of drug-resistant helminths will require strategic evidence-based use, targeted surveillance, and continued research into resistance mechanisms and detection tools.
Abstract
Anthelmintics are central to parasite control in companion animals, but drug targets in helminths remain limited. Anthelmintic resistance is a clinically significant threat, with emerging multiple anthelmintic drug-resistant Ancylostoma caninum, macrocyclic lactone-resistant Dirofilaria immitis and praziquantel-resistant Dipylidium caninum. Each treatment is a selection event which eliminates susceptible parasites and enriches resistant survivors. Drug-resistant helminths often go undetected due to limited diagnostics and sole reliance on treatment. While some molecular tools can detect gene polymorphisms associated with resistance, their use is somewhat limited. Sustainable control will require strategic evidence-based use, targeted surveillance, and continued research into resistance mechanisms and detection tools.
A multidisciplinary and sustainable approach is essential to mitigate the impact of AR and ensure long-term effectiveness of parasite control strategies in small ruminant production systems.
Zeenat Korai, Shahrukh Khan, S. K. Korai et al.· Molecular and biochemical pa...· 2 citations
The epidemiology of the major equine helminths is discussed, current knowledge on anthelmintic resistance is summarised, and practical guidance on implementing sustainable parasite control programmes in clinical practice is provided.
This review summarizes the current progress in nanoparticle-based therapies for parasitic worm infections, discusses the advantages and limitations of different nanocarrier systems, and highlights the challenges and prospects for translating nanomedicine into effective clinical and veterinary applications.
Harmanjot Kaur, Lachhman Das Singla, Diptiman Choudhury· Journal of Animal Biology an...· 0 citations
Toxoplasma gondii is one of the most important parasites globally in both veterinary and human medicine, with significant impacts on livestock. Approximately one-third of the global population is latently infected. In humans, infection is typically asymptomatic or causes mononucleosis-like symptoms, but primary infecti...
Overall, this review provides a comprehensive overview of T. nativa biology, ecology, and diagnosis, while emphasizing future research priorities to improve early detection, epidemiological monitoring, food safety, and the effective management of trichinellosis in endemic regions.
A. Zhumalin, A. Gajimuradova, Saulet Issayev et al.· Veterinary World· 0 citations
Selective deworming may be risky for foals, as parascarids can cause obstructive ileus in young animals with high infection rates, and in farms with a high prevalence of parascaridiasis, deworming should be performed even at low egg counts in feces to prevent acute cases and animal deaths.
N. A. Gavrilova· International Journal of Vet...· 0 citations
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