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Review Sep 2026

Beyond monoculture limits: a critical review of yeast co-cultures for xylitol production from lignocellulosic biomass

Key synergistic mechanisms, including in situ detoxification, parallel utilization of pentose and hexose mixtures, and metabolite exchange (cross-feeding), which distribute metabolic functions among specialized strains, expanding metabolic diversity and optimizing carbon valorization, are analyzed.

W. Monroy-Martínez, J. C. González-Hernández, M. C. Chávez-Parga · 0 citations
Open access Aug 2026

REGULATION OF METABOLIC PATHWAYS TO ENHANCE RIBOFLAVIN BIOSYNTHESIS IN EREMOTHECIUM ASHBYI

Riboflavin is one of the most important water-soluble vitamins involved in numerous biochemical processes in living organisms. It serves as a precursor of the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which are essential cofactors for enzymes involved in the electron transport chain,...

Z. Shopova · 0 citations
Sep 2026

Metabolic Engineering of the Thermophilic Fungus Myceliophthora thermophila for l -glutamate Production from Lignocellulosic Biomass

l-Glutamic acid is conventionally produced by bacteria from starch-derived sugar, while its production in eukaryotic hosts remains rarely reported. The thermophilic ascomycete fungus Myceliophthora thermophila has been developed as a platform for producing value-added chemicals from lignocellulosic biomass. In this s...

De-Fei Liu, Yu-Tong Ge, Jin-Gen Li et al. · 0 citations
Open access Aug 2026

Carbon source–driven metabolic and regulatory remodeling defines phenomic states in Lipomyces starkeyi

A suite of multi-omic data is collected to dissect how carbon source availability reshapes the metabolic network, lipid allocation, and regulatory architecture of Lipomyces starkeyi and enhances the understanding of Lipomyces molecular rearrangements.

L. Monteiro, Xiao-Lu Li, Kyle R. Pomraning et al. · 0 citations
Review Open access Aug 2026

Advances in glycerol metabolism comprehension in yeasts: from regulation to metabolic engineering strategies

This review addresses current knowledge on the regulatory networks controlling glycerol metabolism in yeasts, compassing transport mechanisms, metabolic pathways, transcriptional control and enzyme regulation, and pointed out promising avenues for future research and biotechnological innovation.

Juliana Silva Carneiro Fonseca, W. B. da Silveira · 0 citations
Open access Sep 2026

Systematic metabolic engineering of Yarrowia lipolytica for highly efficient biosynthesis of mannitol from glucose.

Mannitol is widely utilised in the food and pharmaceutical industries. Current commercial production primarily depends on chemical synthesis, a process that is expensive, environmentally detrimental, and requires high-temperature/pressure as well as complex purification steps. While microbial production of mannitol has...

Yue Zhang, Shuo Xu, Tong Li et al. · 0 citations

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