TL;DR
A non-linear, U-shaped pattern of association was observed between PA frequency and digestive cancer risk, most pronounced in men and in individuals who had never smoked, which should be interpreted cautiously given the potential for residual confounding and exposure misclassification.
Highlights • Meeting the recommended weekly LTPA volume was associated with lower mortality.• Frequency and intensity subgroup analyses were exploratory and underpowered.• Findings support a cautious, volume-focused interpretation for survivorship care.
Even light-to-moderate alcohol consumption was associated with increased CRC risk; therefore, strict restriction of alcohol intake may help reduce this risk, particularly among individuals with IFG or diabetes.
Background: To assess the association of sedentary time and physical activity with the occurrence of colorectal adenomas in asymptomatic participants. Methods: We conducted a case-control study at Taipei Veterans General Hospital, Taiwan, to examine sedentary time, physical activity, and their joint effects on colorect...
Gender-specific analyses revealed higher tobacco smoking-attributable PAFs in young men and higher obesity-related PAFs in young women, contributing to understanding the distinct etiology of early-onset CRC and highlighting the need for age-specific prevention strategies.
In a direction-of-effect synthesis, healthy dietary exposures were protective in 9 of 9 estimates, whereas smoking and unhealthy diets were predominantly associated with increased risk.
Abstract Background Previous research on moderate-to-vigorous physical activity (MVPA) and ovarian cancer risk have shown inconsistent results. Most studies measured recreational MVPA once during late adulthood, which does not consider the way in which timing may differently influence risk or account for MVPA from othe...
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