The Lifespan Architecture of Human EEG

Heterogeneity of brain dynamics in genetic and psychiatric conditions

Whether the heterogeneity of psychiatric conditions converges on shared neurophysiological alterations or translates into distinct signatures remains unclear. We assembled high-density electroencephalogram (hd-EEG) resting-state recordings from 4,812 individuals aged 5 months to 66 years across 11 psychiatric condition...

Lifespan EEG Reference Charts Reveal Aperiodic Confounds in Beta-Band Biomarkers Across Neurological and Neuropsychiatric Disorders

Scale-Dependent Development of Neural Signal Complexity and its Association with Working Memory in Childhood

Brain Network Dynamics of Local and Global Predictive Processing in Aging

ABSTRACT Cognitive aging is widely associated with a progressive weakening of neural responses associated with predictive brain mechanisms. This view is supported by decades of electrophysiological studies reporting attenuated mismatch responses in older adults. Yet the literature remains inconsistent, suggesting that...

Mapping and modulating brain dynamics in aging and neurodegeneration with electroencephalography and integrated neurotechnologies in primates

Non-human primates (NHPs) provide an essential translational platform for investigating neural mechanisms underlying brain aging and neurodegenerative diseases. Their neuroanatomical organization, cortical complexity, and cognitive capacities share close parallels with those of humans, enabling a degree of experimental...

Age-Related Changes in Spontaneous Brain Dynamics Revealed by Resting-State Magnetoencephalography.

Spontaneous neuronal oscillations support large-scale brain communication and are sensitive to adult aging, yet how their moment-to-moment dynamics change across the adult lifespan and relate to cognition remains unclear. Here, we used resting-state magnetoencephalography (MEG) and time-delay embedded hidden Markov mod...