Cerebral white matter lesions (WML) are histopathologically heterogeneous but associated with vascular risk factors and thought mainly to indicate ischemic damage, with aMCI patients having higher risk than naMCI for conversion throughout the 5-year follow-up period.
Visual MRI rating scales are simple, reproducible, and reliable tools for dementia assessment that can be scored on routine MRI without specialized sequences or post-processing, and their correlation with the more sensitive MoCA reinforces their role in clinical evaluation.
Harsh Anand Singh, A. Dwivedi, Abhishek Pathak· The Egyptian Journal of Radi...· 0 citations
WMH baseline and trajectory changes are key risk factors for CN cognitive decline and WMH trajectory changes are linked to cognitive function and brain Aβ deposition.
W. Ba, Cui-Ping Bao, Ying-Xun Gong et al.· Journal of Alzheimer's Disea...· 0 citations
MRI-derived brain-PAD predicts progression to dementia in memory clinic patients with SCD or MCI and provided additional predictive value to visual rating scales in patients with SCD and mild cognitive impairment.
S. de Vries, K. Farkas, Hanneke F. M. Rhodius-Meester et al.· Neurology· 0 citations
Distinct patterns of cerebral perfusion-cognition relationships characterize AD and DLB, reflecting differential regional vulnerabilities underlying cognitive decline, which may contribute to improved understanding of the pathophysiology underlying cognitive decline and support disease monitoring.
Yume Koizumi, Yoshikazu Nakano, Mitsuyoshi Tamura et al.· Journal of Alzheimer's Disea...· 0 citations
Global and occipital PSMD may help identify AD participants with concomitant cerebral amyloid angiopathy (CAA) and DTI‐ALPS indices were associated with preserved language function and memory, and no PSMD metric was associated with any clinical measure.
Debina Laishram, G. Du, Sangam Kanekar et al.· Annals of Clinical and Trans...· 0 citations
MRI measures of cerebral blood flow and white matter hyperintensities differentiated NDAN from AD+MCI, highlighting vascular contributions to cognitive resilience, and CBF differentiated AD+MCI from Controls.
S. Fernandes‐Taylor, I. Driscoll, M. Glittenberg et al.· medRxiv· 0 citations
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