Frequent changes in anti-epileptic drug (AED) regimens are associated with a progressively lower quality of life (QoL), as main outcome measure, in a community-based setting and should be monitored in daily clinical practice.
PURPOSE
Clinical and psychological factors associated with health-related quality of life (HRQoL) in drug-resistant epilepsy (DRE) are well established; however, the contribution of alexithymia and specific neurocognitive domains remains less well characterized. This study aimed to examine clinical, emotional, and neur...
Real-world data indicate that more than half of patients with depression had no observed ADT, highlighting the need for individualized strategies and adherence to clinical guidelines.
Yi-Yan Liu, B. De Los Santos, Michael Kim et al.· Journal of Affective Disorde...· 0 citations
Dose adjustments, particularly dose increases, were associated with a higher frequency of adverse effects, and careful dose optimization may therefore be important to balance tolerability and seizure management.
Y. Nomier, Yaqeen Al-Aamri, Rawan Al-Toqi et al.· Healthcare· 0 citations
While seizures remain a central concern, families prioritize developmental, behavioral, sleep-related, and psychosocial domains nearly as strongly as current care models and literature emphasize HRQoL measurement but rarely capture explicit parental goals.
P. Borusiak, H. Philippi, T. Bast et al.· Epilepsy & Behavior· 0 citations
OBJECTIVE
To investigate the patient-reported antidepressant discontinuation rate after adverse events (AEs) and its associated factors.
METHODS
This retrospective recall-based cross-sectional survey was conducted at Beijing Anding Hospital from April 7, 2025, to January 21, 2026. A total of 500 adult patients (≥18 y...
Qian Zhai, Fang Yan, Han Qi et al.· Psychiatry Research· 0 citations
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