Overall, human organoid and organoid-on-chip platforms expand the experimental toolkit for NTD research and show potential for developmental toxicity assessment, risk‑factor screening, and patient‑specific disease modeling.
Organoids are three‐dimensional multicellular structures derived from stem cells or primary tissues that recapitulate key structural and functional features of native organs. Advances in stem cell biology, biomaterials, and bioengineering have established organoids as powerful platforms for studying human development a...
Yue-Qi Leng, Yue Wang, C. Cao et al.· MedComm· 0 citations
The present narrative review outlines the scientific foundations underpinning organoid development, tracing their emergence from advances in tissue engineering and three-dimensional culture systems, and places particular emphasis on their growing role in precision medicine.
Precise spatial organization of cells is critical for engineering functional tissues and constructing human developmental models. Here, we report the development of acoustic cell patterning (ACP), an ultrasound-based method capable of rapidly generating spatial patterns of multiple cell types on both rigid and complian...
The graphic presented represents a summary of the overall workflow used for creating, characterizing, and medical uses of the brain organoids derived from stem cells, and represents a detailed process of brain organoid research and its application.
H. E. Marei, Anwarul Hasan· Cellular and molecular neuro...· 0 citations
ABSTRACT Brain organoids are self‐organizing 3D aggregates derived from pluripotent stem cells and thus mirror many aspects of human brain development, including gene expression programs, spatial organization, and neuron subtype specification. As a result, these organoids have been used to emulate neurodevelopmental, n...
Aishwarya Pantula, K. Joshi, Swarangi Samant et al.· Advancement of science· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.