TL;DR
A dual-component SPION-based platform improved the functional stability and antibacterial performance of immobilized PlyF307, highlighting its potential for antimicrobial nanobiotechnology applications.
Antimicrobial photodynamic therapy (aPDT) is a promising alternative for combating multidrug‐resistant bacteria and overcoming limitations of conventional antimicrobial treatments. To improve aPDT performance, two Protoporphyrin IX (PpIX) derivatives functionalized with one or two capsaicin fragments were synthesized a...
Escherichia coli-derived l-asparaginase (EcA) is a crucial frontline therapy for the treatment of acute lymphoblastic leukemia (ALL), yet its use in clinical settings remains considerably compromised due to its immunogenicity, hypersensitivity reactions, hepatotoxicity, rapid proteolytic degradation, and a markedly s...
The results demonstrate the potential of microbial bioprocessing in engineering prospective nanotechnological platforms to combat antimicrobial resistance and establish C. lusitaniae as a robust microbial cell factory for synthesizing functionalized CeO₂NPs with potent activity against XDR P. aeruginosa.
The observed physiological and transcriptomic responses provide molecular evidence associated with the improved antibacterial performance of tFNQ and support the potential application of tFNAs-based co-delivery strategies for antimicrobial intervention.
A minimal yet functionally robust branching strategy to construct peptide dendrimers featuring with one or two branched heptapeptides tethered to a linear nonapeptide scaffold, with lauric acid introduced to the dendrimer core to drive self-assembly and enhance molecular stability is presented.
Background/Objectives: In this study, ZIF-8 and silibinin-loaded ZIF-8 nanostructures containing different concentrations of silibinin were successfully synthesized using a one-pot method and characterized by FT-IR, SEM, and EDX analyses. Methods: The antibacterial activities of the synthesized nanostructures were subs...
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