Aug 2026· Adolescência e Saúde· 0 citations· 9 references
TL;DR
A comprehensive narrative review of current AI/DL applications in ultrasound diagnosis, synthesising evidence across four major clinical domains and identifying recurring limitations across the literature - dataset heterogeneity, limited external/multicentre validation, and interpretability gaps - and outlines directions for future research toward clinically deployable, trustworthy AI-assisted ultrasound diagnosis.
Abstract
Ultrasound (US) remains one of the most widely used medical imaging modalities because it is real-time, radiation-free, portable, and comparatively inexpensive, but its diagnostic accuracy is strongly operator-dependent and subject to inter-observer variability. Over the past decade, artificial intelligence (AI) - and deep learning (DL) in particular - has been applied extensively to ultrasound image analysis in an effort to reduce this variability and support faster, more consistent diagnosis. This paper presents a comprehensive narrative review of current AI/DL applications in ultrasound diagnosis, synthesising evidence across four major clinical domains: breast lesion classification, thyroid nodule risk stratification, fetal cardiac screening for congenital heart disease, and abdominal/musculoskeletal applications. A structured review methodology is described, followed by a proposed conceptual framework that organises reviewed applications by deep learning task - classification, detection/localisation, and segmentation - and by clinical domain, situating an explainability layer and human-in-the-loop clinical review at the centre of responsible deployment. Reported diagnostic performance metrics (accuracy, sensitivity, specificity) from a representative set of primary studies and meta-analyses are synthesised and compared, showing that convolutional neural network (CNN)-based models frequently reach or approach expert-level diagnostic performance in constrained, retrospective evaluation settings, with reported accuracies generally in the 88-99% range and reported sensitivities in the 87-98% range across the domains reviewed. All performance figures reported in this paper are drawn directly from the cited primary studies and meta-analyses, not from a new experiment conducted by the authors. The review concludes by identifying recurring limitations across the literature - dataset heterogeneity, limited external/multicentre validation, and interpretability gaps - and outlines directions for future research toward clinically deployable, trustworthy AI-assisted ultrasound diagnosis.
It is highlighted that while AI shows tremendous promise for enhancing diagnostic accuracy and clinical efficiency in ultrasound medicine, successful implementation requires multidisciplinary collaboration, robust validation frameworks, and organizational infrastructure for sustainable clinical integration.
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