Sep 2026· Journal of Biomedical Informatics· pp.
105101
· 0 citations
Medicine
TL;DR
MedAL is a scalable method for fine-tuning LLMs across many health systems without sharing patient-level data, enabling high-performance local models for reasoning over clinical notes and may also be useful for training multimodal healthcare AI models.
CoMedBench is introduced, a reproducible benchmark that evaluates a family of generators under a common clinical-validity framework and one shared training and evaluation engine, spanning static tabular and temporal downstream tasks on established critical-care datasets.
Akanta Das, Farhad Al-Amin Dipto, M. S. Anto et al.· 0 citations
A robust technical framework is established for developing trustworthy, high-efficiency medical AI systems capable of operating entirely within hospital-controlled infrastructure by evaluating the synergistic impact of context window scaling and multi-stage supervised fine-tuning within a localized Retrieval-Augmented...
L. Pawlik, Stanisław Deniziak· Scientific Reports· 0 citations
Findings suggest that drift-triggered temporal and institutional adaptation can improve the robustness and stability of clinical language models under the distribution shifts represented in the evaluated datasets, but further prospective and independent external validation is required before the framework can be consid...
Simultaneous assessment of medical imaging and patient records is often required in clinical diagnosis. However, standard machine learning algorithms cannot analyze these data types together. Meanwhile, compliance with HIPAA and GDPR can constrain centralized aggregation of sensitive patient data. This leaves a crucial...
While general-purpose large language models (LLMs) demonstrate remarkable capabilities, their clinical application demands rigorous adaptation to ensure safety and accuracy. This review presents a comprehensive framework for transforming LLMs into trustworthy medical specialists. We detail three core knowledge-injectio...
Kiduk Kim, Jeong Min Song, Dong Yeong Kim et al.· Cell Reports Medicine· 0 citations
This work introduces and evaluates a privacy-preserving knowledge distillation framework for LLM-based clinical modeling, using multimorbidity scoring as a healthcare task, and establishes a trustworthy, privacy-compliant pathway for large-scale healthcare applications of LLMs.
R. Awasthi, Yi-He Yang, Meng-Xuan Li et al.· medRxiv· 0 citations
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