Sep 2026· Advances in Biochemical Engineering/Biotechnology· 0 citations
Medicine
TL;DR
This review discusses the structural diversity and bioactivity of representative tetracyclic and pentacyclic triterpenoids, such as ginsenosides, licorice triterpenoids, mogrosides, saikosaponins, and lupeol-type triterpenoids, and systematically summarizes the key enzyme families involved.
Oleanane-type pentacyclic triterpenoids are a class of naturally occurring specialized metabolites with diverse biological activities. Conventional plant extraction and chemical synthesis are constrained by low yields, high costs, and a reliance on natural resources. With the development of synthetic biology and meta...
Fu-Yan Yuan, De-Yue Diao, Shi-Xiang Peng et al.· Journal of Agricultural and...· 0 citations
This review summarizes recent advances in monoterpenoid biosynthesis, multilevel regulation, and heterologous production, with particular emphasis on major bottlenecks and optimization strategies for sustainable and efficient biomanufacturing.
Jun-Chi Zhang, Jiale Cui, Shang Li et al.· Natural Products and Biopros...· 0 citations
Prenylated stilbenoids are valuable nutraceutical candidates found in dietary plants. Compared to their nonprenylated counterparts, they often exhibit enhanced bioactivities, which are attributed to the increased lipophilicity conferred by the prenyl groups, facilitating their partitioning into cell membranes and inter...
Weiming Lai, Ling-Rong Wen, Yue-Ming Jiang et al.· Journal of Agricultural and...· 0 citations
Covering: 2002-2025Marine fungi have emerged as a prolific source of structurally unprecedented and biologically potent secondary metabolites, and hybrid polyketide synthase-non-ribosomal peptide synthase (PKS-NRPS) enzymes mainly from marine fungi like symbiotic Aspergillus and deep-sea Penicillium, represent an excep...
Ning Gao, F. Owusu, Jie Yu et al.· Natural product reports (Pri...· 0 citations
Plant-derived bioactive compounds, including polyphenols, polysaccharides, alkaloids, terpenoids/saponins, lignans and glucosinolates, are widely valued for their health-promoting potential, yet poor bioavailability and, in several cases, biological inactivity in native form limit their translation into functional...
Ying Ni, Wen-Sheng Zhang, Yao Sun et al.· Journal of Food Bioactives· 0 citations
Flavonoids are polyphenolic natural products predominantly isolated from plants and exhibit a diverse array of biological activities. Because they serve as important pharmaceuticals and nutraceuticals, there is a strong demand for their sustainable supply. Chlorflavonin is a rare fungal flavonoid with potent antituberc...
Sho Furumura, T. Ozaki, Kazuya Hasegawa et al.· Journal of the American Chem...· 0 citations
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