Aug 2026· Journal of Clinical Medicine Research· Vol 18, pp. 515 - 527· 0 citations· 49 references
Medicine
TL;DR
Recent advances in machine learning applications for PCI prognostic prediction are reviewed, encompassing predictive targets including in-hospital mortality, major adverse cardiovascular events, bleeding complications, and long-term survival.
Abstract
Percutaneous coronary intervention (PCI) has become a cornerstone treatment for coronary artery disease; however, accurate prognostic prediction remains a significant clinical challenge. Machine learning technologies demonstrate tremendous potential in PCI prognostic prediction by analyzing vast amounts of clinical data and identifying complex nonlinear relationships among variables. This article systematically reviews recent advances in machine learning applications for PCI prognostic prediction, encompassing predictive targets including in-hospital mortality, major adverse cardiovascular events, bleeding complications, and long-term survival. Algorithms such as random forest, support vector machines, neural networks, and deep learning have demonstrated superior predictive performance compared to traditional risk scoring systems across multiple studies. Deep learning approaches exhibit particular advantages in processing multimodal data. Nevertheless, significant challenges remain regarding model interpretability, external validation, and clinical implementation. Future research should prioritize the development of explainable artificial intelligence systems, the conduct of multicenter validation studies, and the establishment of regulatory frameworks for clinical deployment.
Cardiovascular disease remains one of the leading causes of mortality worldwide, with early detection being crucial for improving patient outcomes. This study aims to develop and validate a machine learning-based prediction model for heart disease using electronic health records from a major hospital system in New Jers...
O. Osama, Daehan Won, M. Khasawneh et al.· IISE Annual Conference &...· 0 citations
There is an urgent need for explainable, clinically validated and standardised ML frameworks to translate predictive models into routine healthcare practice and improve early detection of cardiovascular disease.
Hanna Rasheed, Arya.K.R Arya.K.R, Ashida.K.A Ashida.K.A· International Journal of Tec...· 0 citations
Evidence is provided that ensemble-based frameworks currently offer the most effective balance between predictive accuracy, robustness, and clinical feasibility, and future research should emphasize multi-center external validation and explainable AI frameworks.
Marium Shaikh, Hanmant Fadewar· International Journal For Mu...· 0 citations
Future work should prioritize calibration, robustness, transportability, fairness, interpretability, regulatory clarity, workflow integration, and prospective evidence of decision impact or post-deployment benefit, as well as major barriers remain.
Rui-Feng Liu, R. Arena, V. Vasile et al.· Progress in cardiovascular d...· 0 citations
The findings indicate that tree-based ML models such as Random Forest, XGBoost, and Gradient Boosting shows the strong performance on structured clinical datasets, and ensemble learning models shows the superior performance and generalization capabilities across several distinct datasets.
Anuja Gaikwad, Nilima Kulkarnir· Journal of Intelligent Decis...· 0 citations
Overall, AI outlines the transition from a reactive cardiology model toward a predictive, proactive, and precision-based approach in cardiovascular prevention, with a specific focus on risk stratification, early detection of subclinical disease, and identification of patients most likely to benefit from targeted interv...
Simona Giubilato, L. Granata, S. Petrina· Giornale italiano di cardiol...· 0 citations
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