The Molecular Interplay Between Lipids, Cholesterol and Membrane Hydration Layer.

Water at Lipid Interfaces: Domains and Defects.

The coordination of infrared spectroscopy coupled to attenuated total reflectance (FTIR/ATR) under controlled humidity and temperature conditions allowed to obtain information on the hydration state of lipid systems showing important details in the structure and properties that cannot be ignored to have a complete unde...

Molecular dynamics simulations of a complex plasma membrane reveal finely-tuned sphingolipid hydrogen bonds.

A multi-resolution in silico analysis of a lipid bilayer based on the asymmetric lipid composition of the human erythrocyte plasma membrane, which strengthens recent suggestions that lipid bilayers are finely-tuned molecular assemblies in which atomic interactions play critical roles in maintaining and regulating membr...

Impact of Lipid Composition and Synergistic Effect on Aβ42 Oligomer-Induced Changes in Membrane Conductance and Microviscosity

The results demonstrate that the presence of SM or GM1 within a DOPC/Chol backbone is enough to facilitate Aβ42 interaction with the membrane, as evidenced by increased membrane microviscosity; however, this interaction alone is insufficient to induce permeability-enhancing defects in the membrane.

Dehydration triggers anomalous subdiffusion in biomimetic cell membranes

Exploring the thermodynamic competition between APP C99 dimerization and membrane partitioning in model liquid-ordered and disordered membranes.

Lateral membrane heterogeneity creates distinct lipid environments that modulate both the localization and association of transmembrane proteins. Previous studies have examined how transmembrane proteins partition between ordered and disordered domains, and separate studies have shown that membrane composition can modu...

Spatial Extent and Heterogeneity of Water at Phospholipid Membranes Revealed by Molecular Dynamics.