Genomic characterisation of vancomycin-resistant Enterococcus faecium with Tn1546-plasmid rep17 in obstetrics and gynaecology settings in Algeria

Molecular characterization of vancomycin-resistant Enterococcus faecium and identification of a clinical strain co-harboring the G2505A mutation associated with linezolid resistance from a tertiary hospital in China

ABSTRACT The rise of vancomycin-resistant Enterococcus faecium (VREfm) poses a growing global health threat. This study aimed to characterize the molecular features and resistance mechanisms of clinical VREfm isolates from a Chinese tertiary hospital. Eighteen VREfm isolates were identified using matrix-assisted laser...

A genomic snapshot of hospital-adapted CC17 vancomycin-resistant Enterococcus faecium colonising high-risk patients in Serbia.

Genomic Characterisation of Carbapenem-Resistant Klebsiella pneumoniae and Enterobacter hormaechei Clinical Isolates from Nigeria: Evidence of Resistance, Virulence, and Putative Plasmid-Mediated Gene Sharing

Describing clinically relevant resistance and virulence determinants in three purposively selected carbapenem-resistant Enterobacterales from Nigerian tertiary-care hospitals identifies possible plasmid-mediated gene sharing.

Emergence of optrA-mediated linezolid-resistance in human clinical Enterococcus faecalis: an alert for a shifting resistance landscape in hospitals.

OBJECTIVE The emergence of transferable linezolid resistance genes as optrA represents an increasing concern. This study characterizes the first optrA-positive E. faecalis (Efs) isolates associated with human infections in Portugal, while highlighting undetected colonization as a reservoir for dissemination within heal...

One Health genomic surveillance of Klebsiella pneumoniae in Belgium demonstrates large genomic diversity, presence of ESBLs and carbapenemases and circulation of clones across sectors

The findings demonstrate a genetically diverse K. pneumoniae population alongside the circulation of clinically relevant high-risk lineages across One Health compartments and support integrated genomic surveillance to better understand their dissemination.

Molecular epidemiology and antimicrobial resistance of extended-spectrum beta-lactamase-producing Enterobacter cloacae complex in obstetric and neonatal units in Tanga, Tanzania

Enterobacter cloacae complex (ECC) poses a significant threat to neonatal healthcare, particularly in resource-limited settings. This study aimed at characterizing the molecular epidemiology and antimicrobial resistance of ESBL-producing ECC isolates collected from two hospitals in Tanga. A cross section s...