AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
TL;DR
PCDHGB4 is a potential biomarker for pan-cancer, especially SCC, and may promote tumor progression through oncogenic signaling and modulation of the tumor immune microenvironment.
Objective Despite advances in treatment, small cell lung cancer (SCLC) remains highly aggressive and prone to relapse, leading to poor patient outcomes. Histone HIST1H4L is a key protein that maintains chromatin structure, but its role in SCLC is still unclear. This study aims to define its oncogenic role in SCLC and t...
PAXX is a DNA double-strand break repair factor involved in classical non-homologous end joining. Although elevated PAXX expression has been reported in colon cancer, its functional role and downstream mechanisms in colorectal cancer (CRC) remain incompletely defined. This study investigated the role of PAXX in CRC p...
Background Gastric cancer is a major malignancy with molecular heterogeneity and limited biomarkers for risk stratification and therapeutic guidance. Interferon-stimulated 20 kDa exonuclease-like 2 (ISG20L2), a regulator of ribosome biogenesis, has been implicated in tumor progression, but its relevance in gastric canc...
: Objectives: Neuroblastoma (NB) is a heterogeneous pediatric malignancy driven by both intrinsic oncogenic programs and the stromal microenvironment. However, the critical stromal regulators associated with poor prognosis and metastasis in NB remain poorly characterized. This study aimed to identify key cancer-associa...
PPAP2C exhibits the most significant overexpression pattern across 33 cancer types and was significantly associated with advanced clinical stages and aggressive subtypes (HER2+ and TNBC).
RBM39 plays an important regulatory role in multiple cancers. However, its systematic function across pan-cancer and its specific mechanism in head and neck squamous cell carcinoma (HNSC) remain unclear. In this study, we performed pan-cancer expression and survival analyses based on TCGA and GTEx databa...
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