This study identifies parental mental health and monitoring as critical targets for PSU prevention in youth, while neural connectivity patterns offer potential early detection biomarkers.
Investigation of magnetic resonance imaging-derived neurodevelopmental cortical brain Age Gap Estimate and adverse life events as risk factors of early cannabis initiation suggest that while cortical brainAGE may be somewhat increase vulnerability to adolescent cannabis use in females, its contributions are modest at b...
K. Thiessen, Y. Yu, L. Schmid et al.· medRxiv· 0 citations
Cognitive findings were domain specific, similar to findings in secondhand tobacco: SCS exposed youth showed restricted improvement in attention and inhibitory control by age 17, and public health and policymakers should make efforts to curb youth SCS exposure.
J. Bastien, K. Garcia, A. L. Wallace et al.· medRxiv· 0 citations
Gradients across socioeconomic status (SES) exist across most health conditions. While there has been significant attention devoted to the relationship between SES and physical and mental health, less research has examined how these relate to substance use disorders (SUD). In the current study, we use data from the pro...
Peter B. Barr, Megan E. Cooke, S. Kuo et al.· medRxiv· 0 citations
Adolescent substance use is a major public health concern due to increased risk of future physical and mental health conditions. Fronto-striatal functioning - particularly regarding inhibition and reward processing - may increase vulnerability to high-risk substance use. However, it remains unclear if these neurobiolog...
K. Thiessen, F. Breslin, K. Kerr· medRxiv· 0 citations
PURPOSE
Cannabis use during early adolescence can negatively affect brain development and increase the risk of adverse health. We aimed to examine trends and correlates of cannabis-use susceptibility, a psychosocial receptivity construct capturing openness to future use (i.e., absence of a firm commitment not to use, c...
Zi-Han Tang, H. Dai· Journal of Adolescent Health· 0 citations
By dissecting the genetic liability to SUD and SU and investigating their relationship with BIP, this work finds a genetic signature correlated with substance dependence but not substance use more broadly.
L. Ystaas, P. Parekh, N. Parker et al.· Biological Psychiatry· 0 citations
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