Aug 2026· Folia Microbiologica (Prague)· 0 citations· 120 references
Medicine
TL;DR
A better understanding of the GM-miRNA axis may facilitate the development of novel biomarkers and personalized therapeutic strategies, ultimately shifting MS management from symptomatic treatment toward precision, disease-modifying interventions.
This review synthesizes recent advances in understanding how peripheral immunity and gut microbiota influence neurodegenerative processes, highlighting key signaling pathways and mechanisms and examines current therapeutic strategies.
Vishwadeep Singh, V. Saxena, Sanskriti Upadhyay· Journal of Human Nutrition a...· 0 citations
BACKGROUND
Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system characterized by progressive neuroinflammation and demyelination. Increasing evidence suggests that the gut microbiota contributes to MS pathogenesis through bidirectional gut-brain interactions; however, the underlyin...
Jin-Xin Wang, Fang Zheng, Yu-Chen Zhang et al.· Multiple Sclerosis and Relat...· 0 citations
BACKGROUND AND PURPOSE
Ischemic stroke (IS) remains a leading global cause of mortality and disability. Although current reperfusion strategies have advanced, the complex pathological mechanisms underlying IS continue to significantly limit clinical prognosis. Recently, the pivotal role of the microbiota-gut-brain axis...
Zhengyuan Liu, Xin-Wei Zhao, Ze-Yu Yang et al.· Journal of Stroke & Cerebrov...· 0 citations
Autoimmune encephalitis (AE) comprises a heterogeneous group of inflammatory disorders of the central nervous system mediated by autoimmune responses, involving multiple pathological processes, including autoantibody production, aberrant immune-cell activation, and persistent neuroinflammation. In recent years, accumul...
Hai-Yang Zhang, Xue Zhou, Yu-Gang Ma et al.· Frontiers in Microbiology· 0 citations
The gut microbiota acts as an upstream regulator of AD pathology through interconnected molecular mechanisms, and microbiota-targeted interventions have the potential to modulate these pathways and improve cognitive outcomes, although results vary across studies.
Javeria Fatima, Y. Siddique· CNS and Neurological Disorde...· 0 citations
Parkinson’s disease (PD) is increasingly understood as a multisystem disorder in which gastrointestinal dysfunction, immune remodeling, protein aggregation, and central neurodegeneration interact across the disease course. Although gut microbiota alterations are repeatedly reported in PD, taxonomic differences alone do...
Ming X. Tang, Jing-Xian Li, Chuan-Zhang Zhang et al.· Frontiers in Aging Neuroscie...· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.