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Open access Oct 2026

Ellagic Acid Promotes Repair of Acetic Acid-Induced Oral Ulcers in Rats: Associations with Redox-Inflammatory Responses and STAT3/EGFR Signaling

Oxidative stress and inflammation are central barriers to oral mucosal ulcer repair, yet redox-oriented interventions for recurrent aphthous ulcer (RAU)-relevant injury remain insufficiently defined. Ellagic acid (EA) is a naturally occurring polyphenol with antioxidant and anti-inflammatory activities, but its role in...

Jian-Fa Wu, Ying Cui, Huan Chen et al. · 0 citations
Aug 2026

Yangyin Shengji Powder inhibits inflammation and promotes the wound-healing in oral ulcers through regulating SIRT1/NF-κB p65 signaling pathway.

The findings suggest that YYSJS promotes oral ulcer healing by alleviating inflammation and enhancing cell proliferation, possibly through regulation of the SIRT1/NF-κB p65 signaling pathway.

Hong-Yue Yu, Yun Liu, Limimg Liu et al. · 0 citations
Review Open access Aug 2026

Etiology, Therapeutic Challenges, Drug Interactions, and Future Directions of Gastric Ulcer Progression to Gastric Cancer

Gastric cancer remains one of the leading causes of cancer-related mortality worldwide, and chronic gastric ulceration represents an important precursor lesion in a subset of patients. This narrative review aimed to synthesize evidence published between 2015 and 2026 on the etiology and pathogenesis of gastric ulcer, c...

Hadis Farokhmoradi, Parsa Jahani, S. Saravani et al. · 0 citations
Open access Sep 2026

Plant-Derived Polyphenols in Osteoarthritis: Mechanisms, Delivery Systems, and Therapeutic Synergy

Osteoarthritis (OA) is a common, disabling joint disease characterized by complex inflammatory, oxidative, and catabolic cascades that culminate in progressive cartilage degradation, subchondral bone remodeling, and synovitis. Standard pharmacological treatments such as nonsteroidal anti-inflammatory drugs (NSAIDs) pro...

Mohd Farhan · 0 citations
Review Open access Sep 2026

Herbal Medicine and the Gastrointestinal Microbiota in Gastric Precancerous Lesions and Gastric Cancer: Mechanistic Evidence and Translational Challenges

Abstract Gastric cancer (GC) remains one of the leading causes of cancer-related morbidity and mortality worldwide. Increasing evidence indicates that microbial alterations associated with GC extend beyond Helicobacter pylori (H. pylori) infection and involve coordinated ecological changes across the oral cavity, gastr...

Jing Zhang, Ya-Qun Yao · 0 citations
Review Open access Aug 2026

Alkaloids Mediate Multi-Level Modulation of Gastric Carcinogenesis: From Antibacterial and Anti-Inflammatory Actions to Antitumor Effects

Gastric cancer is one of the malignancies with the highest incidence and mortality worldwide. Helicobacter pylori (H. pylori) infection is the primary driving factor in its development. The progression of gastric mucosal malignancy follows the Correa cascade model: “chronic non-atrophic gastritis → chronic atrophic gas...

Yan-Ting Liu, Zi-Jin Sun, Wangli Ouyang et al. · 0 citations

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