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Integrated network pharmacology and metabolomics reveal the mechanisms of Compound Nanxing Zhitong Plaster in anti-rheumatoid arthritis.

Zhi-Qiang Li Liang Cao Jia-Jia Wang Xia Gao Feng-Tai Suo Feng-Shou Luo Wen-Tao Xu Zhen-Zhong Wang Xin-Zhuang Zhang Wei Xiao
Sep 2026 · Clinical Rheumatology · 0 citations · 46 references
Medicine

TL;DR

CNZP exhibits significant therapeutic effects on RA, potentially by downregulating NOS1 expression and subsequently correcting the metabolic imbalance of L-arginine, and this preclinical study provides mechanistic evidence for the anti-RA effect of CNZP.

DOI PubMed Semantic Scholar
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