TL;DR
LysAEJ demonstrates excellent specificity and antimicrobial activity, making it a promising biocontrol agent against S. aureus and its biofilms in diverse food processing environments.
Lysin LYS176, derived from Staphylococcus aureus (S. aureus) bacteriophage, exerts its bactericidal effect by hydrolyzing peptidoglycan within the bacterial cell wall, leading to rapid cell lysis. Lysin LYS176 exhibited antibacterial activity against 62 strains of S. aureus and maintained strong lytic activity within t...
The potential of SAP_2 as a biocontrol candidate for controlling MRSA contamination in milk is supported and good biosafety and reduced bacterial burdens in MRSA-infected mice are exhibited.
This study depicted and characterized the phage-derived endolysin LysPEF52H, providing a new alternative antimicrobial strategy for controlling bacterial contamination and ensuring food safety. The molecular weight of endolysin LysPEF52H was predicted using an online platform, and its three-dimensional (3D...
The increasing prevalence of antibiotic-resistant uropathogenic Escherichia coli highlights the need for antibacterial strategies that can complement or extend beyond conventional antibiotic treatment. Bacteriophages and phage-derived lytic enzymes represent promising alternatives because of their distinct mechanisms o...
Staphylococcus aureus is an ESKAPE pathogen, defined by its ability to evade antibacterial treatment, and together with S. epidermidis is a leading Gram-positive cause of wound infection. The emergence of methicillin- and vancomycin-resistant strains further limits conventional antibiotic treatment. The staphylococcal...
Staphylococcus spp., other than S. aureus (SOSA, formerly CoNS), are opportunistic pathogens often linked to biofilm infections on indwelling devices. Their rising antibiotic resistance highlights the need for novel therapies. Bacteriophages are promising due to their specificity and ability to inhibit cell growth and...
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