Skip to content
Open access

A foundation model for acute abdomen diagnosis stratification and triage on noncontrast computed tomography

Aug 2026 · Nature Communications · Vol 17 · 0 citations · 44 references
Medicine

TL;DR

A foundation model for non-contrast computed tomography, a multi-task AI system built on a self-supervised foundation model that detects 11 acute abdominal conditions and performs three risk-stratification subtasks from NCCT images is presented.

Abstract

Accurate and timely diagnosis of acute abdominal emergencies remains challenging. Non-contrast computed tomography (NCCT) is often used as an initial imaging modality because of atypical presentations, contraindications to contrast, or resource constraints. Here we present AbdomenNet, a multi-task AI system built on a self-supervised foundation model that detects 11 acute abdominal conditions and performs three risk-stratification subtasks from NCCT images. AbdomenNet is pre-trained on 103,989 NCCT examinations and fine-tuned on 5816 annotated cases. We assess generalizability in 2528 patients from three independent external cohorts, evaluate radiologist performance in a multi-reader multi-case crossover study, and estimate workflow impact using retrospective reconstruction. In external validation, AbdomenNet achieves a macro-average AUROC of 0.919 for five emergent conditions. AI assistance increases radiologists’ mean AUROC from 0.812 to 0.924 and reduces median reading time by 52.5 seconds per case. Workflow reconstruction indicates that AI-driven prioritization could shorten median report turnaround time by 37 minutes. The authors present AbdomenNet, a foundation model for non-contrast computed tomography. It detects 11 acute abdominal conditions, helps identify high-risk cases, improves radiologist accuracy, and may speed emergency reporting.

Read PDF

Similar papers

Open access Sep 2026

An LLM-enhanced AI agent for rapid diagnosis of acute aortic dissection in multi-center settings

Summary Acute aortic dissection (AAD) is a high-mortality cardiovascular emergency, yet early diagnosis before computed tomography angiography (CTA) remains challenging. We developed AAD-Agent as a pre-imaging triage aid—not as a replacement for CTA—and evaluated it in a retrospective, multi-center study. Using 869 sus...

Hu-Nian Li, Yu-Chen Pei, Tao Hu et al. · 0 citations
Open access Sep 2026

Large-scale esophageal cancer screening through noncontrast computed tomography and artificial intelligence.

The absence of accurate, noninvasive, scalable screening tools keeps early esophageal cancer (EC) detection a global health challenge. Although noncontrast computed tomography (NC CT) is widely accessible, the esophagus is a hollow tubular structure prone to collapse and motion artifacts, making small early malignant l...

Jian Zhou, Guangyu Guo, Jia-Wen Yao et al. · 0 citations
Open access Sep 2026

Artificial Intelligence Triage of Urgent Versus Non-Urgent CT Brain Findings to Support Expedited Emergency Department Disposition: A Retrospective Validation Study.

OBJECTIVE Evaluate the diagnostic accuracy of an artificial intelligence (AI) model for identifying urgent computed tomography brain (CTB) findings in consecutive emergency department (ED) patients and estimate the proportion eligible for expedited disposition. METHODS We retrospectively analysed 3424 consecutive non...

Hassan K. Ahmad, Y. Kitzing, Victoria Bond et al. · 0 citations
Review Open access Sep 2026

OPTIMIZATION OF CARDIOVASCULAR DIAGNOSIS THROUGH ARTIFICIAL INTELLIGENCE APPLIED TO THORACIC RADIOLOGICAL IMAGES: A SYSTEMATIC REVIEW OF DIAGNOSTIC PERFORMANCE, GENERALISABILITY AND TRANSLATIONAL READINESS

Background. Cardiovascular disease remains the leading cause of death worldwide, yet risk stratification depends on inputs that are frequently missing in routine care. Chest radiographs and chest computed tomography (CT) are acquired in vast numbers for non-cardiac indications and contain cardiovascular information tha...

Denisse Andrea Puentes Aguila, Ana María Ángel Isaza, Roxana Rivera Valencia et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.