TL;DR
ADC radiomics provided complementary information for differentiating benign and malignant PI-RADS 3-5 prostate lesions, but its incremental value beyond the clinical model was limited.
RATIONALE AND OBJECTIVES The clinical management of Prostate Imaging Reporting and Data System (PI-RADS) 3 lesions remains controversial due to their equivocal likelihood of clinically significant prostate cancer (csPCa). This study aimed to develop and validate a prediction model for csPCa detection to assist in clini...
A minimal-feature radiomics model derived exclusively from ADC images showed promising diagnostic performance for differentiating malignant from benign prostate lesions, and may provide a practical, reproducible, and resource-efficient strategy for supporting prostate cancer diagnosis.
RATIONALE AND OBJECTIVES To develop and validate a quantitative nomogram integrating the intravoxel incoherent motion (IVIM)-derived true diffusion coefficient (D) and prostate-specific antigen density (PSAD) for predicting clinically significant prostate cancer (csPCa) in patients with elevated serum PSA, and to compa...
Purpose To investigate the incremental value of whole-tumor apparent diffusion coefficient (ADC) histogram parameters, when combined with clinical pathological variables for predicting extracapsular extension (EPE) in patients with PI-RADS 4–5 prostate cancer. Methods This retrospective study included 102 patients with...
Background and purpose Primary central nervous system lymphoma (PCNSL) and high-grade glioma (HGG) may share overlapping conventional MRI appearances. We developed and internally validated a parsimonious model combining tumor apparent diffusion coefficient (ADC) and the lipid-to-creatine ratio (Lip/Cr), compared it wit...
Objectives To characterize recurrence heterogeneity among patients with VI-RADS 2 non-muscle-invasive bladder cancer (NMIBC) and to develop and internally validate a recurrence-free survival (RFS) prediction model incorporating quantitative MRI features. Methods This retrospective study included 342 patients with patho...
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