Sep 2026· Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology· Vol 42 9, pp.
798-807
· 0 citations
Medicine
TL;DR
The findings suggest that the adenosine-NT5E/CD73 axis may be a candidate pathway related to immune imbalance in RSA, but the current evidence cannot replace validation of NT5E/CD73 protein expression and spatial colocalization of CD68/CD86/CD206 in patient villous tissues.
CONTEXT
Pre-eclampsia (PE) involves placental dysfunction and immune dysregulation, but the cell-type localization of tryptophan-kynurenine-nicotinamide adenine dinucleotide (Trp-Kyn-NAD+) axis-related genes in PE placentas remains unclear.
AIMS
This study aimed to localize Trp-Kyn-NAD+ axis-related expression across...
Yi Zhang, Xiao-Xiao Lin, L. Yao et al.· Reproduction, Fertility and...· 0 citations
INTRODUCTION/OBJECTIVE
Endothelial dysfunction and altered stromal-immune crosstalk are implicated in chronic inflammatory diseases. However, their roles in atherosclerotic plaque (AP) and premature ovarian insufficiency (POI) remain unclear.
METHODS
The single-cell RNA-seq (scRNA-seq) data of AP and human follicular...
Qian-Qian Ma, Han Zheng, Ai-Ling Chen et al.· Current Medicinal Chemistry· 0 citations
A macrophage-centered anoikis-related immune signature in atherosclerosis is defined and HAVCR2 is identified, together with CD36, PLAU, TNF, PYCARD, SERPINA1, BLNK, and CHI3L1, as potential biomarkers and candidate targets for future diagnostic and therapeutic investigation.
Qiang Shen, Zheng-Feng Fan, Jin-Cheng Hou et al.· Frontiers in Immunology· 0 citations
This hypoxia-associated seven-gene signature showed diagnostic potential and reflected immune and molecular heterogeneity in DKD and was associated with macrophage- and neutrophil-related immune remodeling.
Yue Ji, Jia-Kun Zhang, Xi Guo et al.· Diabetes Research and Clinic...· 0 citations
TSPAN32 is nominated as the primary SCFA-responsive effector gene in intestinal epithelial cells, coordinating epigenetic remodeling and immunometabolic reprogramming and support TSPAN32 as a predicted network-stabilizing node rather than merely a differentially expressed transcript.
Zahra Masood, Iqra Sarwar, Ayesha Sanam et al.· Frontiers in Bioinformatics· 0 citations
Dupuytren’s disease (DD) is a progressive fibroproliferative disease characterized by palmar fascia fibrosis, extracellular matrix deposition, and finger contractures. Reliable diagnostic biomarkers and regulatory mechanisms have not yet been fully defined.
Firstly, integrate the public transcriptome datas...
Xian-Jie Lin, Ming-Min Wang, Yu-Tian Lin et al.· Frontiers in Molecular Biosc...· 0 citations
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