Skip to content

Polygenic risk score for neurodevelopmental disorders and cognitive impairment at long-term follow-up of first-episode psychosis.

Sep 2026 · European Archives of Psychiatry and Clinical Neuroscience · 0 citations · 100 references
Medicine

TL;DR

Evidence is provided for a possible direct genetic effect on cognitive performance for the PRS of common genetic variations related to neurodevelopment and attention deficit hyperactivity disorder in patients with FEP.

View source

Similar papers

Meta-analysis Open access Sep 2026

Circulating BDNF in pediatric neurodevelopmental disorders: a meta-analysis of case–control differences and cognitive severity

Background Brain-derived neurotrophic factor (BDNF) has been proposed as a neuroimmune biomarker of cognitive dysfunction in paediatric neurodevelopmental disorders other than autism spectrum disorder, but two related questions remain poorly characterised: whether circulating BDNF differs between affected and unaffecte...

Begüm Çapa Tayyare, B. Yuksel, Nurullah Eryilmaz · 0 citations
Open access Sep 2026

Common genetic variants are associated with increased likelihood of latent co-occurring neurodevelopmental and mental health factors among autistic individuals.

Evidence is found for additive effects of other genetic factors in contributing to some latent co-occurring neurodevelopmental and mental health conditions in autism.

Adeniran Okewole, Vincent-Raphaël Bourque, M. Koko et al. · 1 citation
Open access Sep 2026

Neurodevelopmental Trajectories and Neurodevelopmental Disorders Following Neonatal Intracranial Hemorrhage: A Long-Term Follow-Up Study and Analysis of Influencing Factors

Background: To investigate the neurodevelopmental trajectories, the incidence of neurodevelopmental disorders, and associated influencing factors in children following neonatal intracranial hemorrhage (ICH), thereby providing a reference for clinical intervention and prognostic improvement. Methods: A total of 80 neona...

Su Lin, Ru-Meng Yu, Zhi-Yong Ding et al. · 0 citations
Open access Sep 2026

Neurocognitive profiles in early childhood in relation to clinical and functional outcomes in middle childhood in offspring at familial high-risk of schizophrenia or bipolar disorder: The Danish High-Risk and Resilience Study.

A significantly impaired neurocognitive profile in early childhood confers risk for detrimental clinical and functional outcomes in middle childhood beyond that which can be attributed to pre-existing clinical and functional states and constitutes a cross-diagnostic, neurodevelopmental risk marker in these FHR-groups.

N. Hemager, J. Jepsen, A. Greve et al. · 0 citations
Open access Aug 2026

Polygenic profiles in youth with early-onset psychosis and offspring of schizophrenia or bipolar disorder patients.

The role of genetic factors shaping liability for psychosis remains unclear. Youth with first-episode, early-onset psychosis and youth at increased familial risk for psychosis show higher rates of co-occurring psychiatric diagnoses and cognitive difficulties than the general population. This study assessed polygenic sc...

I. Martínez-Serrano, A. G. Segura, María Ortuño et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.