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Aug 2026

Loneliness, not isolation, is the missing link between social connectedness and mental health among midlife to older U.S. adults.

OBJECTIVES To investigate whether loneliness or social isolation serves as the main pathway connecting social connectedness dimensions to mental health outcomes among midlife to older adults. METHODS We examined longitudinal data from 4,963 adults aged 40-65 at baseline in the U.S. national MIDUS study (2004-2014). S...

Yu-Tien Hsu, Ester Villalonga-Olives, Bridgette M. Rice et al. · 0 citations
Aug 2026

Family support is important for mitigating the mental health consequences of loneliness among Black Americans at midlife: Results from a longitudinal mediation analysis.

PURPOSE Social connectedness influences mental health, yet pathways through loneliness versus social isolation remain underexamined among Black Americans. This study examines these mediating pathways. METHODS We analyzed longitudinal data (between 2005-2006 and 2016-2017) among Black Americans (N = 592) in the Midlif...

Yu-Tien Hsu, Yusuf Ransome · 0 citations
Open access Sep 2026

Neighborhood physical disorder and social participation among older Americans: mediations of social cohesion and depressive symptoms.

OBJECTIVES This research examined the associations between neighborhood physical disorder and social participation among community-dwelling older adults, and whether low social cohesion, as a social-relational pathway, and depressive symptoms, as a psychological pathway, partially explain the associations. METHODS Us...

E. Cheung · 0 citations
Review Open access Aug 2026

Loneliness, Social Isolation, and Accumulation of Chronic Conditions: A Nationwide Longitudinal Study in Japan.

BACKGROUND Loneliness and social isolation are related but distinct dimensions of social disconnection, but their longitudinal associations with chronic condition accumulation remain unclear in non-Western populations. METHODS We analyzed 8,721 adults aged 18 years or older who completed the 2021 and 2025 waves of th...

H. Ito, S. Okaya, Tatsuya Watanabe et al. · 0 citations

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