EP3 receptor mediates calcium oxalate kidney stone formation via Ca²⁺/AKT and necroinflammation

Jing Leng Yang Li Xue-Qing Tang Zhijie Song Hangyu Lv Huiying Han Na Wen Jinghang Fan Zhang A. Xin Lin Zhang Zhang B. Xin Fa-Bin Zhou Tao Guo Qing Liu Bing Gao

Aug 2026 · Urolithiasis · Vol 54 · 0 citations · 29 references

Medicine

TL;DR

It is demonstrated that the EP3 receptor mediates calcium oxalate kidney stone formation through the Ca2⁺/AKT signaling pathway and necroinflammation through the Ca2⁺/AKT signaling axis.

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