[Myelin oligodendrocyte glycoprotein antibody-associated disease].

Abstract

MOG-antibody-associated disease (MOGAD) is a rare inflammatory demyelinating CNS condition. Diagnosis is based on core clinical symptoms supported by additional clinical/MRI data if necessary, depending on the antibody titer in the blood. The clinical presentation is age-dependent. Due to its recent recognition, management is not clearly defined. Treatment differs from other inflammatory demyelinating CNS diseases such as multiple sclerosis (MS) or neuromyelitis optica spectrum disorder (NMOSD) despite overlapping symptoms. In this review, we summarise recent knowledge for optimal patient management.