Relapse in adult idiopathic inflammatory myopathies: clinical predictors and the potential role of anti-NXP2 in a single-center retrospective cohort study.
Younger age, anti-NXP2 positivity, and IVIG use independently increased relapse risk, whereas long-term maintenance therapy substantially delayed relapse, highlighting the need for long-term immunosuppression and close monitoring of high-risk subgroups.
Background/Objectives: Idiopathic inflammatory myopathies (IIMs) are very rare, chronic, immune-mediated diseases that clinically manifest with myositis symptoms and extramuscular manifestations. The rarity of the disease makes it difficult to conduct double-blind studies, and large population-based studies are needed...
Maria Dutsch-Wicherek, Bartłomiej Wieleba, K. Lewtak et al.· Journal of Clinical Medicine· 0 citations
Background: Idiopathic inflammatory myopathies (IIMs) carry an increased malignancy risk. Although the International Myositis Assessment and Clinical Studies Group (IMACS) has proposed guidelines to screen malignancies, their applicability across populations remains uncertain. In this study, we analysed risk factors fo...
L. Kumari, C. Kavadichanda, Mamatha Gorijavulu et al.· Indian Journal of Rheumatolo...· 0 citations
INTRODUCTION/AIMS
Early recognition and treatment are critical in juvenile myasthenia gravis (JMG), yet pediatric-specific evidence remains limited. We aimed to describe treatment patterns, remission rates, and predictors in a Canadian cohort.
METHODS
We conducted a retrospective study of patients under 18 years diag...
Tanitnun Paprad, E. Nigro, Z. Aleisa et al.· Muscle and Nerve· 0 citations
Patients with anti-SRP-associated NAM were relatively more severe, and cancer screening should be considered in anti-HMGCR patients, and Rituximab was beneficial in individual patients.
Sirilux Angsuwattanakul, Thanes Termglinjan, A. Rojana-udomsart· Journal of Clinical Neuromus...· 0 citations
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