Adaptive DBS is technically feasible and offers a promising approach to individualized stimulation, but its comparative clinical value remains uncertain and larger randomized trials are needed before superiority over conventional stimulation can be established.
Background: Non-invasive brain stimulation (NIBS) is a promising adjunct for Parkinson’s disease (PD), but variation in modality, target, stimulation dose, outcome selection, and safety reporting has produced uncertain estimates of benefit and risk.Objective: To evaluate the efficacy and safety of sham-controlled NIBS...
Kholoud Mousa Abd El-Hamed Soliman· Natural Resources for Human...· 0 citations
Deep brain stimulation (DBS) is one of the most effective surgical interventions for neurodegenerative diseases (NDDs), particularly Parkinson's disease
(PD). Although the technique originated in the 1950s and 1960s to treat chronic pain and psychiatric disorders, modern advancements targeting the
subthalamic nucleus (...
F. A. Yusupov, M. Abdykadyrov· Avicenna Bulletin· 0 citations
BACKGROUND AND OBJECTIVES
This systematic review aims to evaluate the differences in clinical efficacy and quality of life between asleep and awake subthalamic nucleus deep brain stimulation (STN-DBS) procedures in patients with Parkinson's disease.
METHODS
A comprehensive search was conducted in PubMed/Medline, Emba...
Malene Mikkelsen, Katrine Sværke, Sine Fjeldhøj et al.· Neurosurgery· 0 citations
Transcranial alternating current stimulation (tACS) is a promising noninvasive intervention for modulating pathological brain oscillations in Parkinson's disease (PD). To evaluate its clinical and neurophysiological efficacy, we searched five databases (Web of Science, PubMed, Scopus, Google Scholar and APA PsycInfo) u...
T.-T. Mai, T. Gjishti, K. Witt et al.· medRxiv· 0 citations
Current evidence indicates that self-regulation of disease-relevant neural signals is feasible in at least a subset of patients, but clinical effectiveness remains uncertain because of small samples, methodological heterogeneity, and limited replication.
Pierluigi Diotaiuti, Francesco Di Siena, Salvatore Vitiello et al.· Frontiers in Neurology· 0 citations
Current randomized evidence suggests that rTMS and tDCS may improve depressive symptoms in patients with PSD and appear generally well tolerated, however, the certainty of these findings is limited by substantial heterogeneity, small sample sizes in several trials, and variation in stimulation protocols.
Pei-Zhang Huang, Hao-Jie Wang, Chen Huang et al.· Frontiers in Psychology· 0 citations
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