This review comprehensively examines recent advancements in dendrimer-mediated delivery systems, elucidating their capacity to optimize solubility, enhance bioavailability, and facilitate the site-specific targeting of therapeutic payloads and offers crucial insights into overcoming translational bottlenecks in targeted therapy.
Dendrimer-based systems have shown considerable potential to remodel the tumor microenvironment, induce immunogenic cell death, enhance immune activation, and facilitate combination therapies, offering promising opportunities to improve cancer diagnosis, treatment, and patient outcomes.
Mahsa Hasannejad Alibaglou, Zeinab Chaharlashkar, Fateme Bina et al.· BioNanoScience· 0 citations
Dendrimers are highly branched nanoscale macromolecules with precisely tunable architectures that have emerged as transformative tools in cancer research. Their unique properties, such as high drug-loading capacity, multivalency, and surface tailoring ability, enable innovative applications in drug delivery, gene thera...
Davood Zaeifi, K. Jamialahmadi, G. Karimi· Biomaterials Science· 1 citation
This review delivers a rigorous and comprehensive systematic overview of contemporary ChNP fabrication methodologies alongside their primary medicinal applications, focusing on targeted drug delivery, oncological interventions, and the treatment of diverse pathological conditions via intrinsic antimicrobial pathways.
E. Gomaa· Russian journal of bioorgani...· 0 citations
This review examines the main classes of nanoplatforms currently explored for cancer therapy, including inorganic, polymeric, lipid-based, and hybrid organic–inorganic systems, and considers emerging directions in AI-guided nanoparticle engineerization design and natural-compound-based nanomedicines, both of which are...
C. Boncristiani, F. Baldassarre, Khadija Eddahaoui et al.· Materials· 0 citations
Boron-containing compounds have emerged as versatile building blocks in the design of advanced anticancer drug delivery systems due to their unique chemical features, including electron deficiency, reversible covalent interactions, and structural diversity. In recent years, significant progress has been made in enginee...
Current preclinical evidence supports nanomedicine as a central pillar of precision drug delivery, with future progress expected to focus on adaptive, multifunctional, and patient-specific platforms that align with the principles of personalized medicine.
Ashna Sureshkumar, P. Balu· Frontiers in Biomaterials Sc...· 0 citations
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