These findings identify phase-specific functional biomarkers of aphasia recovery beyond traditional clinical measures, highlighting multiple-demand and inferior frontal regions as candidate targets for phase-adapted neurostimulation approaches.
MRI is an excellent tool for monitoring functional and structural network reorganization after brain injury and may provide biomarkers for treatment stratification and novel neuromodulatory interventions. In ischemic stroke, functional network changes, particularly within the contralesional hemisphere, and structural i...
F. Mahani, G. R. Fink, M. Hoehn et al.· bioRxiv· 0 citations
Background People with chronic stroke retain the capacity to learn new motor skills, yet how preserved motor learning is expressed during practice remains incompletely understood. Sequence learning provides a useful model for examining these within-session learning dynamics and their neural basis after stroke. Objectiv...
Kirstin-Friederike Heise, Patricia Finetto, P. McConnell et al.· bioRxiv· 0 citations
The adult brain follows normative aging trajectories, yet stroke abruptly disrupts this process. Beyond the focal lesion, undamaged regions can deviate from expected aging due to diaschisis or pre-existing vulnerabilities, reflecting tissue health that may constrain recovery. Chronic post-stroke aphasia, a persistent l...
Nicholas Riccardi, Ansley Martin, I. Rangus et al.· Journal of Neuroscience· 0 citations
Abstract Predicting the recovery of post-stroke aphasia, particularly in the chronic phase, poses significant challenges. While many studies have focused on static resting state functional connectivity measures as biomarkers for language recovery, there is a significant lack of studies investigating dynamic functional...
I. Falconer, M. Varkanitsa, A. Billot et al.· Brain Communications· 0 citations
Pure alexia (PA) is an isolated reading impairment following brain damage, yet the mechanisms underlying reading recovery remain unclear. We present a Korean patient with PA following a posterior cerebral artery infarction who showed severe impairment in Hangul reading despite preserved writing and spoken language, wit...
Yoonhye Na, Y. Hwang, S. Pyun· Cognitive Neuropsychology· 0 citations
Post-stroke aphasia is a disabling disorder of language and communication for which speech-language therapy remains the standard of care. Because behavioural treatment yields variable gains and many people retain chronic communication limitations, non-invasive neuromodulation has been investigated to increase the respo...
Mariagiovanna De Luca, Giovanni Federico, Daniela Rigatti et al.· Frontiers in Human Neuroscie...· 0 citations
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