An automated assay platform that robustly quantifies antibodies against up to 100 antigens in a single reaction, using Luminex suspension array technology, alongside generating ample quality control measures is described.
Extractable nuclear antigen (ENA) antibody testing is universal to the diagnosis of systemic autoimmune rheumatic diseases (SARDs). However, current commercial multiplex platforms require expensive instruments and are often cost-prohibitive for routine testing in low- and middle-income settings. Pictor PictHealth® Immu...
Jung-Hyun Rho, Andrea Kinga, B. Shetty et al.· JIM - Journal of Immunologic...· 0 citations
The utility of a scalable bead-based platform for high-resolution immune monitoring in CAR-T therapy is demonstrated and baseline TGF-β1 is identified as a candidate exploratory biomarker associated with CRS severity and clinical outcome.
Keyuan Pu, Wanying He, Jiayi Feng et al.· Chemical Science· 0 citations
A rapid, proof-of-concept microfluidic assay for cancer biomarker quantification and functional therapy evaluation that requires only 5 µL of sample, eliminates tedious sample manipulation, and uses commercial antibodies to track both biomarker concentration and functional activity.
Shaked Doron, Lev Brio, Matan Krasner et al.· Biosensors· 0 citations
The multiplex‐bead immunoassay is characterized by its ability to detect multiple analytes simultaneously within a short timeframe and with high precision. Consequently, it is an appealing tool for identifying humoral immune responses to various targets, particularly respiratory viral infections that pose a significant...
Tarfa A. Altorki, M. Basabrain, Abdulaziz Kulthum et al.· Journal of Immunological Res...· 0 citations
Meningitis and encephalitis necessitate rapid pathogen identification to guide therapy, as conventional methods are time-consuming. This study evaluated both the wet-lab analytical performance and the clinical performance evaluation of the Bioeksen Meningitis/Encephalitis Panel (BS-MEP) integrated onto the fully automa...
Mesut Yilmaz, N. Mahroum· Microorganisms· 0 citations
A critical analysis of recent strategies that have been developed to improve the sensitivity of aptamer‐based LFAs and the emerging transition from passive biological selection to active molecular engineering is discussed, outlining the future trajectory of ultra‐sensitive next‐generation LFAs.
Aylar Eslami Saed, Jacopo Giaretta, Syamak Farajikhah et al.· Visual Information Expert Wo...· 0 citations
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