Aug 2026· Zhonghua wei zhong bing ji jiu yi xue· Vol 38 8, pp.
735-743
· 0 citations
Medicine
TL;DR
A stage prediction model for sepsis-associated acute kidney injury (SA-AKI) based on interpretable machine learning is developed, thereby providing support for individualized clinical intervention.
A CatBoost-based machine learning model incorporating 32 clinically accessible variables showed good predictive performance for in-hospital mortality in patients with diabetes and SA-AKI, supporting early risk stratification and clinical decision-making.
Yan-Ni Wang, Hongjie Shen, Sheng-Ze Wu et al.· Journal of Intensive Care Me...· 0 citations
AIMS/BACKGROUND
Sepsis is a leading cause of morbidity and mortality in intensive care units (ICUs). Early identification of patients at high risk of death is essential to guide timely interventions and optimize resource allocation. This study aimed to develop and validate an interpretable machine learning model for pr...
Zhang-Cong Lu, Ling-Han Hu, Peng-Fei Shui et al.· British journal of hospital...· 0 citations
We developed and externally validated an interpretable machine-learning model for observed continuous renal replacement therapy (CRRT) initiation in sepsis-associated acute kidney injury (SA-AKI) using a strict 24-hour landmark framework. This multicenter retrospective study used MIMIC-IV and eICU-CRD data. Predictors...
Yao-Yao Tang, Shuai Zhang, Qiu-Jun Wang et al.· Clinical and Experimental Me...· 0 citations
Abstract Background Sepsis-induced coagulopathy (SIC) is a common and severe complication in patients with sepsis, characterized by microvascular thrombosis, systemic endothelial damage, and markedly increased short-term mortality. Existing traditional clinical risk scoring systems demonstrate limited accuracy and fail...
Jia-Xuan Sun, Jing-Yuan Wang, Yu-Xin Dong et al.· JMIR Medical Informatics· 0 citations
An interpretable Random Forest model employing eight routinely available indicators accurately predicts AKI in septic MM patients, bridging algorithmic complexity and bedside applicability, and may facilitate early risk stratification and personalized renal protection in this high-risk group.
BACKGROUND
Early mortality risk stratification remains challenging in intensive care unit (ICU) patients with acute upper gastrointestinal bleeding (AUGIB). We developed a parsimonious, interpretable ensemble model and evaluated its performance across independent ICU cohorts.
METHODS
MIMIC-IV was used for model devel...
Jian-Shan Shi, Yan-Fen Li, Wen-Xuan Li et al.· International Journal of Med...· 0 citations
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