Impact of severe postoperative complications on oncologic outcomes after curative resection for stage I-III colorectal cancer: a multicenter study.

S. Hashimoto T. Tominaga Keisuke Noda T. Shiraishi Hiroki Katayama Shoko Tei Taiji Hida Kazuki Motoyama Shoto Yamazaki Takashi Ohnoda Hiroshi Maruta Yuma Takamura R. Ono Nobuhito Ogata M. Hisanaga Mitsutoshi Ishii Masaaki Moriyama H. Fukuoka Ka-Zuo To Kaido Oishi T. Nonaka K. Matsumoto

Aug 2026 · Japanese Journal of Clinical Oncology · 0 citations

Medicine

TL;DR

CD ≥3 complications independently worsen RFS, OS, and CSS but do not significantly affect TTR after curative resection for pStage I-III CRC, suggesting that severe complications may not primarily accelerate recurrence itself, but may instead impair survival after recurrence, highlighting possible mechanisms beyond direct recurrence acceleration.

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