A READ-derived response-associated gene signature for recurrence stratification and exploratory cross-cohort evaluation in additional colorectal cancer cohorts, while further exploring its association with treatment-response phenotypes.
Shuai Li, Jing-Xian Li, Xianyue Bu et al.· Human Cell· 0 citations
It is suggested that IL1RAP and IRF2BP2 may be important in immune-related and candidated biomarker identification in breast cancer PDOs, and an integrated transcriptomic, enrichment and network-based analyses for a robust strategy for biomarker discovery are integrated.
S. Scippa, A. Balestrieri, M. Zanfardino et al.· Frontiers in Bioengineering...· 0 citations
BACKGROUND
Ovarian cancer (OC) recurrence and therapy resistance remain major clinical challenges. Identifying the molecular adaptations associated with relapse is essential for improving disease monitoring.
RESEARCH DESIGN AND METHODS
We performed miRNA expression profiling on tissue and serum samples obtained from...
Ece Gumusoglu-Acar, Kaan Kara, S. Topuz et al.· Epigenomics· 0 citations
Bulk deconvolution analysis identifies subtype-specific methylation differences in pancreatic cancer patients and suggests that there are substantial epigenetic changes at the methylation level that contribute to the biological phenotypes of the PDAC subtypes not captured at the transcriptional level.
Erin E. Grundy, Margaret A. Hall, Y. Yoo et al.· Cancer Research· 0 citations
IntClust can be inferred from routine clinical sequencing and resolves survival heterogeneity not captured by ER or HER2, and reveals subtype-specific contexts for prognostic effects of the same mutation drivers, and for acquisition of ESR1 mutations.
A. Yaacov, A. Grinshpun, P. Pharoah et al.· medRxiv· 0 citations
