Semaglutide Alleviates LPS-Induced Cognitive Disorder via O-GlcNAcylation of AKT-mTOR Signaling Pathway Components

Qiangwei Liu Lu Chen Mengxue Zhang Zhun Wang Xiaokun Wang Ying Dong Kaiyuan Wang Changyu Jiang Yiqing Yin

Aug 2026 · Neuromolecular medicine · Vol 28 · 0 citations · 77 references

Medicine

TL;DR

Semaglutide ameliorates PND via AKT O-GlcNAcylation-mediated AKT-mTOR activation and subsequent neuroprotective effects and rescued synaptic plasticity.

DOI PubMed Semantic Scholar

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