Longitudinal changes in serum taurine following acute traumatic spinal cord injury: a prospective pilot study of diagnostic performance and functional recovery.
Aug 2026· European spine journal· 0 citations· 7 references
Medicine
TL;DR
Serum taurine decreases following acute traumatic SCI, increases during recovery, and demonstrates good diagnostic performance with significant associations with functional outcomes, supporting its potential as a biomarker for injury severity and neurological recovery.
Blood-based combinations of IFN-γ, IL-8 and IL-6 and CSF-based combinations of IFN-γ and IL-10 were associated with admission injury severity, and only GFAP in blood retained a consistent association with follow-up neurological status when accounting for admission injury severity.
K. A. Aagaard, T. O. Wichmann, C. V. B. Hviid et al.· Journal of Clinical Medicine· 0 citations
Serum NSE is a promising neurochemical biomarker for differentiating patients with traumatic TSCI from healthy controls, particularly when interpreted alongside complementary biochemical markers includes LDH, CRP, CK, WBC, Hb, and glucose.
Mustafa Alburhan, Razzaq Sachit, Ameer Aa Aldafaay· Libyan Journal of Applied an...· 0 citations
Background: Traumatic brain injury (TBI) is a significant public health concern. Mild to moderate TBI often receives less attention, even though it can result in substantial functional impairment. Inflammatory biomarkers, such as C-reactive protein (CRP), are believed to serve as predictors of neurological outcomes and...
Evita Jodjana, J. M. Pertiwi, Denny J. Ngantung et al.· Glosains Jurnal Sains Global...· 0 citations
OBJECTIVES
This prospective, longitudinal cohort study investigated cognitive functioning acutely and up to 6 months after pediatric mild traumatic brain injury (mTBI) relative to orthopedic injury (OI).
METHODS
Children age 8-17 years with acute (≤48 hours) mTBI or OI were consecutively recruited from five pediatric...
Michael A. Lee, K. Yeates, M. Beauchamp et al.· Journal of the International...· 0 citations
Objective: To test the accuracy of existing traumatic brain injury (TBI) outcome prediction models in older adults with TBI (oaTBI), to determine the independent association of five different measures of pre-injury health with 6-month outcome, and to investigate whether these pre-injury health measures improve outcome...
Roy Tzemah-Shahar, Y. Rosen-Lang, A. Puccio et al.· The journal of head trauma r...· 0 citations